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PEER-REVIEW | SKIN REJUVENATION |


Figure 1 (A) Before combination treatment with Hybrid Energy and injections of hyaluronic acid, and (B) 10 days after second treatment


effect. The skin generates a healing process leading to fibroblast activation and promotes the production of new collagen and hyaluronic acid. The microneedles penetrate the skin enabling efficient,


Figure 2 (A) Before treatment with Hybrid Energy for peri-orbital wrinkles and lack of volume, and (B) 1.5 months after three treatments


Figure 3 (A) Before treatment with Hybrid Energy for neck skin tightening, and (B) after 6 treatments


uniform, and homogenous penetration coverage with minimal to no pain or bleeding. HE (microneedles and electrical energy) creates invisible microwounds in the dermal layer characterized by optimal dermal impact and minimal epidermal effect. The microwounds are surrounded by healthy unaffected skin areas, which function as healing centers promoting effective neocollagenesis and skin renewal. The Hybrid Energy treatment triggers the body’s natural healing response mechanism in a safe and effective process, with minimal pain and side-effects. The combination of RF and an additional non-thermal


electrical energy enhances skin penetration as well as the clinical effect and wound healing process. An increased energy input is achieved without increasing RF heating but through a chemical reaction. The electrical energy stimulates a chemical reaction between the skin’s fluids and salts. A controlled, mild change of pH (generating an alkaline environment due to generation of OH), occurs in the dermis. This chemical change creates fractional, cold electro-coagulation zones in the tissue. The electrical effect and the RF thermal effect both


energy applied directly to the specific target area,


enhancing the total clinical effect. The result is dermal volumizing through targeted thermal skin restructuring reinforced by deep volume refilling. A typical treatment starts with cleansing the treatment


area but does not require a numbing cream or local anesthesia. The energy is delivered via an array of microneedles


0.6 mm in length. There are two types of needle tips: 6x6 microneedles (total of 36) or 6x2 microneedles (total of 12) to treat small focused and delicate areas. The RF energy may be adjusted according to the individual’s needs by controlling the power (up to 62 mJ/pin) and the exposure time (units in ms). Pulses may be overlapped, and several passes may be performed. The penetration of the needles with the radiofrequency energy, followed by an electrical current create a wound


A typical


treatment starts with cleansing the treatment area but does not require a numbing cream or local anesthesia.


Figure 4 (A) Before treatment with Hybrid Energy, (B) a slight erythema is visible immediately after the treatment that (C) subsides one hour later


generate an ongoing skin healing process, involving fibroblast activation, promoting production of new collagen and hyaluronic acid. The procedure, therefore, benefits from two types of minimal invisible micro ablation ‘generators’ affecting the skin and causing the required trigger to stimulate natural healing and skin renewal. Recently, three peer reviewed papers were published; the


first, ‘Ex vivo study of hybrid energy technology using a human skin model’, published in the European Journal of Dermatology, 2014, validated significant collagen remodeling and an increase in hyaluronic acid with the use of hybrid energy20


. In other words, natural volume achieved from


within together with a significant increase in epidermal renewal. The second study, ‘VoluDerm microneedle technology for skin treatments — in vivo histological evidence’, published in the Journal of Cosmetics and Laser Therapy, 2015, presented immediate epidermal and dermal effects and complete healing of the ablation zones after 14 days for all energy levels21


. In the third and final study,


‘Voluderm microneedle technology for treating skin laxity and wrinkles — initial clinical experience’, published in Jacobs Journal of Experimental Dermatology, 2015, Dr. Shapiro shares his clinical experience and concludes that


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August/September 2015 | prime-journal.com


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