This page contains a Flash digital edition of a book.
38 CHROMATOGRAPHY


The Azura Compact Bio has a new refractive index detector


By conjugating Dox with polyglutamate, drug developers can target its uptake by cancer cells; Omnisec quantifi es the amount of Dox in the conjugate and elucidates changes in structure that occur as a function of drug loading, thereby enabling researchers to optimise drug delivery performance.


The Omicron Camag Derivatizer aims to give user-independent results


T e Omnisec’s two key attributes are its great measurement sensitivity, providing reliable data with less sample weight (the molecular weight distribution of a sample can be measured with as little as 100ng of material) and its wide range of light scattering detectors.


New peripherals Also in the SEC arena, the Azura Compact Bio LC 10 is a fast protein liquid chromatography (FPLC) system that supports all glass columns on the market. It features a buff er pump that provides pressures up to 50 bar and enables fast separations. With an electrical injection valve, a variable wavelength UV detector and a robust fraction collector, automated SEC purifi cation can be implemented with very high precision. T e new RID 2.1L refractive index detector enhancement to the Compact Bio is suitable for detecting compounds with little or no UV activity, such as alcohols, sugars, lipids or polymers and can be used for both analytical HPLC and GPC applications. T e diff erential refractometer’s wide linear dynamic range of up to 2,000 µRIU and maximum fl ow rate of 10 ml/min also make it suitable for most LC tasks. T e unit’s smart temperature


control ensures high sensitivity, fast baseline stabilisation and solid reproducibility, while the long-life LED, highly pressure- resistant fl ow cell and enhanced diagnostics functions provide easy handling and minimal maintenance. In the area of high-


performance thin-layer www.scientistlive.com


chromatography (HPTLC), Omicron’s new Camag Derivitizer can cut out the need for an experienced analyst to carry out derivitization, the process that enables substances without chromophores or colour to be visualised, making them detectable. T e Camag Derivitizer is an intuitive spraying device for the automated derivatization of TLC plates, designed to ensure homogeneous and reproducible application of the most common reagents. It utilises an innovative ‘micro droplet’ spraying technology, which uses four diff erent colour-coded spray nozzles, adjustable to six spraying levels. T e closed system aims to give user- independent results and keep costs down; when compared to the dipping of TLC plates the Derivitizer uses much less reagent (2-4mL per plate) while considerably reducing the relative standard deviation of manual spraying from up to 12% down to the region of 4.5%. Omicron sees the new


derivitizer as an asset to labs working in such diverse areas as food and environmental science, pharmaceuticals, forensics and cosmetics as well as clinical and medical environments.


Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36  |  Page 37  |  Page 38  |  Page 39  |  Page 40  |  Page 41  |  Page 42  |  Page 43  |  Page 44  |  Page 45  |  Page 46  |  Page 47  |  Page 48  |  Page 49  |  Page 50  |  Page 51  |  Page 52  |  Page 53  |  Page 54  |  Page 55  |  Page 56  |  Page 57  |  Page 58  |  Page 59  |  Page 60  |  Page 61  |  Page 62  |  Page 63  |  Page 64  |  Page 65  |  Page 66  |  Page 67  |  Page 68  |  Page 69  |  Page 70  |  Page 71  |  Page 72  |  Page 73  |  Page 74  |  Page 75  |  Page 76