SUPER-RESOLUTION MICROSCOPY continued a b


Figure 1 – Comparison of imaging at the diffraction limit vs using super-resolution microscopy. Both (a) and (b) show the same growth cone NG-108, with F-actin in green and tubulin in red. (a) was captured using confocal microscopy; (b) was captured using super-resolution microscopy. (Images courtesy of Kaoru Kato, National Institute of Advanced Industrial Science and Technology [AIST], Biomedical Research Institute, University of Tsukuba, Graduate School of Life and Environmental Sciences, Japan.)


a b


Figure 2 – Stress fibers in a HeLa cell, depicting F-actin (phalloidin 488) and Myosin IIb (Alexa 568). a) Spinning-disk-confocal image. b) Images of the same specimen using the Olympus SD-OSR spinning-disk super-resolution system. (Images courtesy of Keiju Kamijyo, Tohoku University School of Medicine, Japan.)


AMERICAN LABORATORY


26


MARCH 2016


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