» SPECTROSCOPY 4.
»
Bakeev KA, Chimenti RV. Pros and cons of using correlation versus multivariate algorithms for material identification via handheld spectroscopy. Eur Pharm Rev. 2013. Available at:
http://media.europeanpharmaceuticalreview.com/wp-content/uploads/Bakeev-Web- Article_proof.pdf. Accessed November 18, 2014.
5.
Kalyanaraman R, Ribick M, Dobler G. Portable Raman spectroscopy for pharmaceutical counterfeit detection. Eur Pharm Rev. Non-destructive Materials Identification Supplement 2012;17(5):11–15. Available at:
http://www.europeanpharmaceuticalreview.com/wp- content/uploads/Raman-Supplement-2012.pdf. Accessed November 18, 2014.
6.
Kauffman J, Gryienwicz-Ruzicka CM, Arzhantsev S, et al. Pharmaceutical surveillance with rapid spectroscopic screening technologies. Am Pharm Rev. 2010;13(1):58-64. Available at:
http://www.americanpharmaceuticalreview.com/Featured-Articles/117601- Pharmaceutical-Surveillance-with-Rapid-Spectroscopic-Screening-Technologies/. Accessed November 18, 2014.
7.
Mungikar A, Kamat M. Use of In-line Raman spectroscopy as a non-destructive and rapid analytical technique to monitor aggregation of a therapeutic protein. Am Pharm Rev. 2010;13(7):78-83. Available at:
http://www.americanpharmaceuticalreview.com/ Featured-Articles/37071-Use-of-In-line-Raman-Spectroscopy-as-a-Non-destructive- and-Rapid-Analytical-Technique-to-Monitor-Aggregation-of-a-Therapeutic-Protein/. Accessed November 18, 2014.
8. 9.
De Beer T, Burggraeve A, Fonteyne M, Saerens L, Remon JP, Vervaet C. Near infrared and Raman spectroscopy for the in-process monitoring of pharmaceutical production processes. Int J Pharm. 2011;417(1-2):32-47.
Thomas RJ, Bakeev KA, Claybourn M, Chimenti RV. The use of Raman spectroscopy in cancer diagnostics. Spectroscopy. 2013;28(9):36-43. Available at: http://www.
spectroscopyonline.com/spectroscopy/Articles/The-Use-of-Raman-Spectroscopy-in- Cancer-Diagnostic/ArticleStandard/Article/detail/822977. Accessed November 18, 2014.
10.
Fenn MB, Xanthopoulos P, Pyrgiotakis G, Grobmyer SR, Pardalos PM, Hench LL. Raman spectroscopy for clinical oncology. Advances in Optical Technologies. 2011;2011:1-20. Available at:
http://www.hindawi.com/journals/aot/2011/213783/. Accessed November 18, 2014.
11. 12. 13.
Jing N, Lipert RJ, Dawson GB, Porter MD. Raman nanoparticle probes for antibody-based protein detection in tissues. Anal Chem. 1999:71(21):4903–4908.
Tu Q, Chang C. Diagnostic applications of Raman spectroscopy. Nanomedicine. 2012;8(5):545–558.
Choo-Smith LP, Edwards HGM, Endtz HP, et al. Medical applications of Raman spectroscopy: from proof of principle to clinical implementation. Biopolymers. 2002;67(1):1–9.
14. Granger JH, Granger MC, Firpo MA, Mulvihill SJ, Porter MD. Toward development of a surface enhanced Raman scattering (SERS) based cancer diagnostic immunoassay panel., Analyst. 2013;138(2):410–416.
15. Horsnell JD, Smith JA, Sattlecker M, et al. Raman spectroscopy—a potential new method for the intra-operative assessment of axillary lymph nodes. The Surgeon. 2011;10(3):123–127.
16. Horsnell JD, Stonelake P, Christie-Brown J, et al. Raman spectroscopy—a new method for the intra-operative assessment of axillary lymph nodes. Analyst. 2010;135:3042-3047.
17. 18. 19.
Cao G, Hajisalem G, Li W, Hof F, Gordon R. Quantification of an exogenous cancer biomarker in urinalysis by Raman spectroscopy. Analyst. 2014;139:5375-5378.
Casero RA, Pegg AE. Spermidine/spermine N1-acetyltransferase—the turning point in polyamine metabolism. The FASEB Journal. 1993;7(8):653-61.
Pegg AE. Spermidine/spermine-N1-acetyltransferase: a key metabolic regulator. Am J Physiol Endocrinol Metab. 2008;294:E995–E1010.
20. Wallace HM, Fraser AV, Hughes A. A perspective of polyamine metabolism. Biochem J. 2003;376(Pt 1):1-14.
21. Aversa G, Bux R, Cheng B, Ramjiawan B, Sitar DS. Monoclonal antibody for acetylamantadine—Canadian Patent Application No. 2,835,506, Chinese Patent Application No. 201280024582.6, European Patent Application No. 12782078.5. United States Patent Application No. 14/116,743.
22.
Bras A, Sitar DS. A method for assaying the activity of spermidine/spermine N1- acetyltransferase - PCT Application No. PCT/CA2012/050828.
14 | | January/February 2015
23. Gordon R, Cheng DB, Bux R, Ramjiawan B, Ahmed A, Hof F. Detection and quantification of acetylamantadine in urine samples—PCT Application No. PCT/CA2014/050273.
24. 25. 26. 27. 28. 29. 30.
Cheng B. An immunological assay to detect and quantify acetylamantadine in a patient— United States Provisional Patent Application No. 61/871,642.
Pabbies A, Blakley B, Bras A, Sitar DS. (2005). Salivary and urinary excretion of acetylamantadine in patients with head and neck cancer.
Residents’ Research Day— Otolaryngology, St. Boniface Hospital Research Centre, May 20; 2005; Winnipeg, Manitoba.
Sitar DS, Bras AP, Maksymiuk A, Pabbies A, Brandes L, Blakley BW. Amantadine acetylation as a biomarker for malignancy. Clin Pharmacol Ther. 2006;79(2) P10, PI–12.
Sitar D, Bras AP, Maksymiuk A, Pabbies A, Brandes L, Blakley BW. Amantadine acetylation and malignancy. Molecular Medicine Tri-Conference; Febuary 28—March 2; 2007; San Francisco, CA.
Sitar DS, Bras AP, Maksymiuk A, Pabbies L, Brandes L, Blakley BW. (2008). Amantadine acetylation in cancer patients and utility as a diagnostic biomarker. World Conference on Clinical Pharmacology and Therapeutics; July 30; 2008; Quebec City, QC.
Sitar DS, Bras AP, Maksymiuk A, Cheng, KM, Zhou H. Progress in the development of SSAT1 activity as a biomarker for diagnosis of cancer. BIT Life Sciences 2nd World Cancer Congress Proceedings; June 22-25; 2009; Beijing, China.
Lim KLH. Urine test could catch lung cancer early, Chemistry World. 5 September 2014(30).
31. McNay G, Eustace D, Smith WE, Faulds K, Graham D. Surface-enhanced Raman scattering (SERS) and surface-enhanced resonance Raman scattering Applications. Appl Spectroscopy. 2011;65(8):825–837.
(SERRS): A Review of
32. Kneipp K, and Kneipp H. Single molecule Raman scattering. Appl Spectrosc. 2006;60(12):322A-334A.
33. Hoppmann EP, Yu WW, White IM. Inkjet-printed fluidic paper devices for chemical and biological analytics using surface enhanced Raman spectroscopy. Journal of Selected Topics in Quantum Electronics. 2014;20(3):195-204.
34. Hoppmann EP, Yu WW, and White IM. Highly sensitive and flexible inkjet printed SERS sensors on paper. Methods. 2013;63(3):219-224.
Author Biographies
Robert V. Chimenti currently holds the position of Sr. Strategic Applications Engineer at Innovative Photonic Solutions, focusing on laser- based spectroscopy applications with a particular emphasis on Raman spectroscopy. He has earned a MS in Electro-Optics from the University of Dayton and has 10 years of experience in the fields of spectroscopy and laser technology. Additionally, he is an Adjunct Professor in Rowan University’s Department of Physics and Astronomy teaching photonic-based courses.
James Elliott, BSc, BASc, MESc, is currently an engineering consultant at BioMark Diagnostics Inc., responsible for device development and commercialization. Mr. Elliott’s engineering efforts in the medical device industry since 1988, have allowed for a wide range of novel product realizations in the diagnostics and therapeutics sectors. Most recently, Mr. Elliott has worked through Innovative Photonic Solutions to innovate a p-SERS device to be used in Cancer detection applications.
Rashid A. Bux is the founder and CEO of BioMark Diagnostics Inc. Previously he co-founded and served as COO of Optima Health and KKT Spine Centers. He earned a MBA from the University of Western Ontario, and was a medical student at Nairobi University prior to perusing a business degree. Mr. Bux has co-authored several articles and holds numerous patents related to cancer diagnostics and therapeutics applications.
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54 |
Page 55 |
Page 56 |
Page 57 |
Page 58 |
Page 59 |
Page 60 |
Page 61 |
Page 62 |
Page 63 |
Page 64 |
Page 65 |
Page 66 |
Page 67 |
Page 68 |
Page 69 |
Page 70 |
Page 71 |
Page 72 |
Page 73 |
Page 74 |
Page 75 |
Page 76