CATTLE RAISERS COMMUNITY
®
150 mg/mL ANTIMICROBIAL NADA 141-328, Approved by FDA For subcutaneous injection in beef and non-lactating dairy cattle only. Not for use in female dairy cattle 20 months of age or older or in calves to be processed for veal.
(gamithromycin)
Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. READ ENTIRE BROCHURE CAREFULLY BEFORE USING THIS PRODUCT.
INDICATIONS ZACTRAN is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis in beef and non-lactating dairy cattle. ZACTRAN is also indicated for the control of respiratory disease in beef and non-lactating dairy cattle at high risk of developing BRD associated with Mannheimia haemolytica and Pasteurella multocida.
CONTRAINDICATIONS As with all drugs, the use of ZACTRAN is contraindicated in animals previously found to be hypersensitive to this drug.
WARNING: FOR USE IN CATTLE ONLY. NOT FOR USE IN HUMANS. KEEP THIS AND ALL DRUGS OUT OF REACH OF CHILDREN. NOT FOR USE IN CHICKENS OR TURKEYS. The material safety data sheet (MSDS) contains more detailed occupational safety information. To report adverse effects, obtain an MSDS or for assistance, contact Merial at 1-888-637-4251.
RESIDUE WARNINGS: Do not treat cattle within 35 days of slaughter. Because a discard time in milk has not been established, do not use in female dairy cattle 20 months of age or older. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.
PRECAUTIONS The effects of ZACTRAN on bovine reproductive performance, pregnancy, and lactation have not been determined. Subcutaneous injection of ZACTRAN may cause a transient local tissue reaction in some cattle that may result in trim loss of edible tissues at slaughter.
ADVERSE REACTIONS Transient animal discomfort and mild to moderate injection site swelling may be seen in cattle treated with ZACTRAN.
EFFECTIVENESS The effectiveness of ZACTRAN for the treatment of BRD associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni was demonstrated in a field study conducted at four geographic locations in the United States. A total of 497 cattle exhibiting clinical signs of BRD were enrolled in the study. Cattle were administered ZACTRAN (6 mg/kg BW) or an equivalent volume of sterile saline as a subcutaneous injection once on Day 0. Cattle were observed daily for clinical signs of BRD and were evaluated for clinical success on Day 10. The percentage of successes in cattle treated with ZACTRAN (58%) was statistically significantly higher (p<0.05) than the percentage of successes in the cattle treated with saline (19%). The effectiveness of ZACTRAN for the treatment of BRD associated with M. bovis was demonstrated independently at two U.S. study sites. A total of 502 cattle exhibiting clinical signs of BRD were enrolled in the studies. Cattle were administered ZACTRAN (6 mg/ kg BW) or an equivalent volume of sterile saline as a subcutaneous injection once on Day 0. At each site, the percentage of successes in cattle treated with ZACTRAN on Day 10 was statistically significantly higher than the percentage of successes in the cattle treated with saline (74.4% vs. 24% [p <0.001], and 67.4% vs. 46.2% [p = 0.002]). In addition, in the group of calves treated with gamithromycin that were confirmed positive for M. bovis (pre-treatment nasopharyngeal swabs), there were more calves at each site (45 of 57 calves, and 5 of 6 calves) classified as successes than as failures. The effectiveness of ZACTRAN for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica and Pasteurella multocida was demonstrated in two independent studies conducted in the United States. A total of 467 crossbred beef cattle at high risk of developing BRD were enrolled in the study. ZACTRAN (6 mg/kg BW) or an equivalent volume of sterile saline was administered as a single subcutaneous injection within one day after arrival. Cattle were observed daily for clinical signs of BRD and were evaluated for clinical success on Day 10 post-treatment. In each of the two studies, the percentage of successes in the cattle treated with ZACTRAN (86% and 78%) was statistically significantly higher (p = 0.0019 and p = 0.0016) than the percentage of successes in the cattle treated with saline (36% and 58%).
Marketed by Merial Limited 3239 Satellite Blvd., Duluth, GA 30096-4640 U.S.A. Made in Austria
®ZACTRAN is a registered trademark of Merial Limited. ©2012 Merial Limited. All rights reserved. Rev. 03/2012
INDUSTRY ALLIED
Vermeer Reveals New Mower Conditioner Line
V
ERMEER OFFERS A NEW MOWER CONDITIONER LINE THAT COMBINES EXCEPTIONAL productivity, fl exibility and convenience into a powerful package. With 3 models available – the MC2800, MC3300 and MC3700 Mower
Conditioners – operators can get the right machine with the features they need to complete their job in their way. “At the heart of these mower conditioners is the new Q3™ Cutter Bar,
and we’re excited about the capabilities this cutter bar offers – includ- ing lower horsepower requirements, shear protection and more,” says Phil Egging, Ver- meer product man- ager. “This line also
offers the unique Vermeer-designed suspension system, giving operators the opportunity to experience this proven technology from our trailed mower line with a conditioner option.” The modular, shaft-driven Q3 Cutter Bar helps make this line more
fuel-effi cient with minimal gear-to-gear interface, requiring less horse- power than gear bed style cutter bars. Practical innovations, including the Quick-Clip®
Blade Retention System and Quick-Change™ Shear Ring,
make the tasks of changing blades and repairing a sheared device quick and simple. “The Quick-Clip Blade Retention System is something that’s been around
on our cutter bars for some time, and it’s all about ease of maintenance,” says Egging. “Combine that with the shear protection of the Quick-Change Shear Ring, the quick oil check on top of each disc module and the ability to easily access the cutter bar with the lightweight, spring-loaded hood, and these mower conditioners offer ultimate convenience when it comes to maintenance and repair.” The new mower conditioners are equipped with a nitrogen-charged
accumulator suspension system to provide a consistent weight on the cut- ter bar through the full range of motion. Operators can easily customize suspension settings for their specifi c fi eld conditions with a simple turn of a lever, resulting in less cutter bar weight on the ground and less stress on the header and framework when compared to traditional mechanical spring systems. With the option of either a steel roller or v-tine conditioner on all mod-
els, operators can choose the conditioning method preferred for their op- eration. In addition, multiple swath adjustments give users more control over their windrow formation. The line offers cutting widths of 9.1 feet (2.8 m) on the MC2800, 10.5
feet (3.3 m) on the MC3300, and 12 feet (3.7 m) on the MC3700. To learn more about the MC2800, MC3300 and MC3700 Mower Conditioners, visit
vermeer.com.
ZACTRAN-PI-thirdpage-MBovis_THE
CATTLEMAN_FA.indd 11/3/13 11:38 AM 26 The Cattleman November 2013
thecattlemanmagazine.com
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