AN OVERVIEW OF GENOMIC MEDICINE FROM GENES TO GENOMES:


By Ghazi O. Tadmouri,Centre for Arab Genomic Studies,Dubai, UAE


HISTORICAL PRIMER Human gene research commenced in the middle of the last century with many studies aiming at the detection of the various mutations in DNA in order to facilitate sub-classification, prognosis, and monitoring response to therapy for


22 www.lifesciencesmagazines.com


“In the Arab world, there are ongoing efforts to complete sequencing genomes of Arab individuals”


common inherited disorders. A milestone in that process was the work of Dr. Linus Pauling and his colleagues in 1949, who introduced the term ‘molecular disease’ in the medical vocabulary and linked for the first time the specific genetic mutation in patients with sickle cell disease to a single


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