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ISSUE 113 AUGUST/SEPTEMBER 2010 CONTENTS The universe in a C shell NEWS


Plant species research aided by modelling; informatics platform introduced at London hospital; Accelrys completes merger with Symyx


INFORMATION OVERLOAD 8


Felix Grant looks at how statistics packages can be applied to data mining


COPING WITH GENOMICS 12


Greg Blackman assesses the impact on data volumes of the emerging fi eld of genomics


MODELLING FOR HUMANS 16


Paul Schreier explores the capabilities now available in human biological modelling


NEW PRODUCTS DIARY DATES SUPPLIERS’ DIRECTORY INSIDE VIEW


Simon Wood, director of marketing and training for Starlims


39 45 45 46 HPC Products


A brief update of the latest HPC software and hardware


Storage plans


Paul Schreier on improving links between storage data and memory


Beyond the skies 32


Stephen Mounsey on the application of HPC technology to astrophysics and cosmology


HPC Director


Dona Crawford, associate director for computation at Lawrence Livermore National Laboratory


EDITORIAL AND ADMINISTRATIVE TEAM Editor: Warren Clark (editor.scw@europascience.com) Features Writer: Greg Blackman (greg.blackman@europascience.com) Assistant Editor: Stephen Mounsey (stephen.mounsey@europascience.com) Specialist Reporters: Felix Grant, Paul Schreier Product Manager: Viv Ruskin Subscriptions: viv@europascience.com Production: Darren Price


ADVERTISING TEAM Advertising Sales: Darren Ebbs (darren.ebbs@europascience.com) Tel: +44 (0) 1223 211180 Fax +44 (0) 1223 211107 Advertising Production: Jennie Caley (jennie.caley@europascience.com) Tel: +44 (0)1223 477411 Fax: +44 (0)1223 574817


CORPORATE TEAM Chairman and Publisher: Dr Tom Wilkie Chief Operating Offi cer: Mark Rosselli Web: www.scientifi c-computing.com


SUBSCRIPTIONS: Free registration is available to qualifying individuals (Register online at http://www.scientifi c-computing.com). Subscriptions £100 a year for six issues to readers outside registration requirements. Single issue £20. Orders to ESL, SCW Circulation, The Spectrum Building, The Michael Young Centre, Purbeck Road, Cambridge CB2 8PD, UK. Tel: +44 (0)1223 211170. Fax: +44 (0)1223 211107. ©2010 Europa Science Ltd. Whilst every care has been taken in the compilation of this magazine, errors or omissions are not the responsibility of the publishers or of the editorial staff. Opinions expressed are not necessarily those of the publishers or editorial staff. All rights reserved. Unless specifi cally stated, goods or services mentioned are not formally endorsed by Europa Science Ltd, which does not guarantee or endorse or accept any liability for any goods and/or services featured in this publication. US copies: Scientifi c Computing World (ISSN 1356-7853/USPS No 018-753) is published bi-monthly for £100 per year by Europa Science Ltd, and distributed in the USA by DSW, 75 Aberdeen Rd, Emigsville PA 17318-0437. Periodicals postage paid at Emigsville PA. Postmaster: Send address corrections to Scientifi c Computing World PO Box 437, Emigsville, PA 17318-0437.


36 27 32 4 The computer as healer HPC PROJECTS


A section for users and managers of HPC systems


HPC News


The latest news in high-performance computing


22 20 16 LEADER


Diversity in science The breadth of topics that Scientifi c Computing World covers on an issue- by-issue basis is highlighted in the range of articles in this edition. From the exploration of the universe, to the analysis of DNA strands, computing has made such a difference to the scientifi c research process that it seems impossible to imagine how any science was ‘done’ before computers came along. In terms of size, the universe is fi nite but unbounded; in terms of research possibilities, it is all but limitless. High-performance computing has made projects about which scientists of a generation ago could only dream into a reality, as Stephen Mounsey discovers on page 32.


The science of DNA, by contrast, has only been in existence for 60 years, and researchers are still only at the beginning of their journey of discovery. It’s already a decade since the Human Genome Project was completed, and the cost of sequencing a complete human genome has plummeted to around $10k – largely thanks to the sophistication of scientifi c computing, as Greg Blackman explores on page 12. Arguably as complex as the universe, and constructed on the building blocks of DNA, is the human body itself. Software has had its part to play here as well, with the medical profession now able to simulate the impact of various conditions on humans via biological modelling. The effect on diagnosis and treatment could be staggering, as Paul Schreier investigates on page 16. To keep up to date with the latest news and applications of scientifi c computing, be sure to sign up to our free email newsletters, SCNewsline and HPCNewsline, by subscribing at www.scientifi c-computing.com/subscribe. Warren Clark


Cover: Montage by David Houghton Not your copy? Subscribe online for FREE at www.scientifi c-computing.com/subscribe www.scientifi c-computing.com SCIENTIFIC COMPUTING WORLD AUGUST/SEPTEMBER 2010 3


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