Contents
DDW the quarterly business review of drug discovery & development
Publisher and Editor-in-Chief Robert Jordan
Robert@rjcoms.com
Digital & Circulation Manager Giles Jordan
Consultant Editor Dr Roger Brimblecombe
Design & Production Melissa Chadderton
rhubarbcreative@sky.com
Editorial Advisors Dr Steve Arlington Dr Nigel Brown Dr Rathnam Chagaturu Dr David Clough Dr Richard Eglen Dr Gregory Lennon Dr Keith Mansford Dr Stephen Naylor Dr George Poste Dr Amber Salzman Dr David U’Prichard Dr Timothy Wells Dr Rene Ziegler
Drug Discovery World (ISSN 14694344) is published quarterly by RJ Communications & Media Ltd, 39 Vineyard Path, London SW14 8EL, United Kingdom. Tel: +44 (0)20 8487 5656 Fax: +44 (0)20 8487 5666 E-mail:
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d r u g d i s c o v e r y wo r l d contents VOLUME 19 ISSUE 2 ● SPRING 2018
Introduction Dr Roger Brimblecombe Consultant Editor
Informatics Artificial Intelligence and BioPharma R&D IT The PRISME Forum
Therapeutics Bringing IO Together: How an Immunologist and Oncologist Collaborate in an Emerging Field Dr Julia Schuler and Dr Louise Brackenbury
Drug Discovery The Cancer Conundrum – Increasing Clinical Success by Implementing Improved Methodologies in Early Phase Drug Discovery Using Primary Cells and 3D Culture Models to Enhance Cancer Drug Discovery Lubna Hussain
Informatics Driving Strategic Improvements in Biologics Drug Discovery With Scientific Informatics Dr Andrew LeBeau
Business Disruptive Approaches to Accelerate Drug Discovery and Development Part 1: Tools, Technologies and the Core Model Ibis Sánchez-Serrano, Dr Tom Pfeifer and Dr Rathnam Chagaturu
Drug Discovery Kinases – Old Dogs and New Tricks – Application of New Assay Technologies to Shed Light on Kinase Drug Discovery Dr Gary Allenby
Genomics How High-Throughput CRISPR is Set to Deliver Knockout Performance in Drug Discovery Dr Paul Avery and Dr Richard Massey
Therapeutics Natural Born Killers – How Natural Killer Cell Therapy Will Transform Imunotherapy Dr Azuza Tanaka and Dr Michael Seiler
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Front cover illustration courtesy of Mikkel Juul Jensen/Science Photo Library Drug Discovery World Spring 2018 5
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