Contents
DDW the quarterly business review of drug discovery & development
Publisher and Editor-in-Chief Robert Jordan
Robert@rjcoms.com
Digital & Circulation Manager Giles Jordan
Consultant Editor Dr Roger Brimblecombe
Contributing Author Dr John Comley
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Dr Rathnam Chagaturu Dr David Clough Dr Richard Eglen Dr Gregory Lennon Dr Keith Mansford Dr Stephen Naylor Dr George Poste Dr Amber Salzman Dr David U’Prichard Dr Timothy Wells Dr Rene Ziegler
Drug Discovery World (ISSN 14694344) is published quarterly by RJ Communications & Media Ltd, 39 Vineyard Path, London SW14 8ET, United Kingdom. Tel: +44 (0)20 8487 5656 Fax: +44 (0)20 8487 5666 E-mail:
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dr ug discov er y wor ld contents
VOLUME 18 ISSUE 3 ● SUMMER 2017 Introduction
Dr Roger Brimblecombe Consultant Editor
Therapeutics Tackling Multi-Drug Resistant Bacteria Dr Ankit Mahadevia
ADME/Tox
Advancing the Drug Discovery Pipeline With Early Stage in vitro ADME and Toxicity Testing Dr Maureen Bunger
Pharmacogenomics
Long-Read Sequencing Offers Path to More Accurate Drug Metabolism Profiles Dr Jenny Ekholm
Sample Management
New Approaches to Sample Identification Tracking and Technologies for Maintaining the Quality of Stored Samples Dr John Comley
Therapeutics
Raising the Bar on the Biologics Potential Dr Michael Mouradian
Therapeutics
The Rise of Immunotherapies – Strategies to Accelerate Their Advance Into Clinical Trials Edward Cribb
Informatics
UX Design – Maximising the Value of Scientific Software in Life Science R&D
Dr Jennifer A. Cham and Katrina Costa Therapeutics
The Importance of Heterocyclic Compounds in Anti-Cancer Drug Design Simon Pearce
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Front cover illustration courtesy of Dr Terry Beveridge, Visuals Unlimited/Science Photo Library Drug Discovery World Summer 2017 5
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