Sample Management
sLiconic Instruments (
www.liconic.com) is known worldwide as a leading manufacturer of automated plate, tube and vial stores for life science sample management. Liconic offers built ‘fit-for-purpose’ storage solutions addressing current applications in biobanking, cell-based drug screening, genomics, proteomics, diagnostics and precision medicine. The expanded use and application of biological-based materials for life science R&D and healthcare methods demands more critical scrutiny of their temperature sensitivities and more precise temperature control of those materials within a given application. More precise tempera- ture tracking of individual samples is indicated. ID tracking within automated systems is a well-devel- oped technique, the most popular current method employing 1D and 2D barcode labelling with opti- cal reading. In addition to overcoming potential optical-based reading limitations such as interfer- ence from moisture (eg condensation, frost) and/or barcode flaws, wireless MEMS-based tracking technologies can precisely link the sample and its unique temperature history data. Currently, actual sample temperature in most applications is only inferred from temperature monitoring in the devices involved in any given process. The MEMS technology allows for direct, real-time interroga- tion at the level of the actual sample or the rack containing the sample. Liconic can now configure any of its storage systems to incorporate MEMS ID and tracking technology – from small capacity, multi-climate option plate storage and incubators, to its larger-scale, application-rich, sample storage systems (room temperature down to -196˚C). This can provide direct, unambiguous temperature data for a sample within a temporal process or over an archival storage period (Figure 19).
TTP Labtech (
www.ttplabtech.com) is an innova- tive supplier of automated laboratory systems including storage, nL liquid handling and detection systems. TTP Labtechs offer modular, high-density storage systems in the product families of comPOUND and arktic,
utilising 2D barcoded Figure 19
Integrated STC7k5-ULT -80˚°C storage system from Liconic Instruments which can be configured to incorporate a multi-vial rack MEMS reader
negative results from a screen. Additionally, the ability to reduce the amount of sample required to produce a screening result can enable the screening of rare compounds or compounds produced from low-yield synthesis reactions. With the launch of the new sample tube compatible with Echo liquid handlers planned for 2018, Labcyte intends to transform compound management and significant- ly improve the quality and reliability of screening programmes (Figure 18).
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tubes for secure sample tracking with temperature options from ambient to -80˚C. Tube racks are used for input and output of samples but not stored giving unrivalled storage capacity per m2, rapid cherry picking and the avoidance of rack edge effects during freezing for improved sample integrity. Modular storage units offer simple scala- bility and a range of accessories providing future- proof paths to automation including the comPILER fully-automated storage tube to assay plate processing system. The storage
systems Drug Discovery World Summer 2017
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