Sample Management
Figure 17
(Left panel), Labcon 2mL MEMS-enabled cryovials with 2D codes. (Right panel)
Labcon’s new 10x10, Multi-Vial MEMS reader
to produce
Figure 18
Labcyte’s 96-well acoustic tube and tube rack compatible with Echo liquid handlers
innovative, value-added, MEMS- based consumables that help sustain sample qual- ity and chain of custody for both biobanking and compound storage customers. This leading-edge product line can track the ID of each sample, record all temperature excursions experienced during the lifecycle of each sample, and perform consistently at temperatures down to -200˚C, +2˚C. Additional features include the ability to perform high-temperature sample tracking and auditing where temperatures can reach +100˚C, such as in qPCR. Labcon also offers MEMS- enabled data tracking tools such as single-vial and multi-vial benchtop scanners, handheld mobile readers along with software that easily integrates into biobanking or compound storage systems. As researchers continue to develop new biological entities (NBEs) or advanced therapies derived
from human cells, their efforts create samples that are extremely high in value, many are irreplace- able, and all of these constructs are very sensitive to temperature change. When Labcon MEMS- enabled consumables are deployed as a system, with their peripheral readers, transport appli- ances, and inventory software packages, they pro- vide excellent custodial tracking and maintain the highest sample quality possible irrespective of the temperature excursions experienced by the sam- ples (Figure 17).
Labcyte (
www.labcyte.com) in collaboration with Brooks Life Science Systems and AstraZeneca recently reported on its progress to develop a sam- ple tube that will be compatible with its Echo® Acoustic Liquid Handlers at the 2017 Society for Laboratory Automation and Screening Conference. The adoption of Echo Liquid Handlers to transfer samples and reagents into assay plates for miniaturised high-throughput screening and lead optimisation has improved the efficiency and reliability of screening programmes throughout large pharma and life science research. These improvements are largely a result of the Echo system’s ability to transfer nanolitre volumes of samples and reagents without the use of tips or contact of any kind. The development of a sample tube that is compatible with acoustic liquid han- dling will enable Echo system users to transfer samples into assay-ready plates without requiring the samples to be in a microplate first. The use of tips and plates just to prepare samples for transfer on Echo systems will be eliminated. This will also eliminate any risks from leachates or sample reten- tion errors in tips that can lead to false positive or
38 Drug Discovery World Summer 2017
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