digestible amino acids, peptides and polypeptides of short chain length, and glutamine, so it is highly recommended for animal feed (Figure 1). There is also yeast mannan oligosaccharide (MOS, an effective tool in preventing diarrhea caused by contamination of Salmonella and E. coli.), and high levels of β-glucans (immunostimulant, and activates the T-cells present in the gut, triggering the activation of the innate immune system).
Figure 1. RNA Hydrolysis from Saccharomyces cerevisiae yeast.
The results showed (Table 2) that the supplemented sows had
a positive effect on milk production (7.33 kg or 4.82%, on average) and the total concentration of RNA in milk (0.277 mg/mL or 34.2%, on average, at 11 days), which consequently increased the number of piglets weaned (0.68 or 7.31%, on average), the BW of the litter at weaning (1.59 kg or 2.83%, on average), body weight gain (BWG) of the litter at weaning (1.79 kg or 4.70%, on average) and reduced mortality (real -3.80% or -43.28%, on average) in relation to the control un-supplemented group. Hilyses®
can be used as a tool in sow’s diets combining the
nutritional benefits of helping the transmission of nucleotides by milk and reducing mortality and improving the performance of piglets at weaning. However, Hilyses®
also contains the intracellular content, which is fully In order to understand the benefits of Hilyses® , Vitagliano et al.
(2014) studied its supplementation in sows diets at 4 levels of inclusion (0, 4, 8 and 12 kg/MT) since 3 days prior the farrowing until piglets 21 days of age (at weaning). The number and body weight (BW) of piglets at birth were equalized by sow and treatment (number of piglets per sow: 10.48, initial piglet weight: 1.70 kg, litter weight/sow: 17.79 kg). Samples of colostrum and milk were taken to analyze the total amount of RNA present (Table 1).
Table 1. Total RNA concentration (mg/mL) in colostrum and milk of sows
Samples 0
Colostrum 1.28 0.81b
Milk day 11
Milk day 20
0.78b
Hilyses® 4
1.33 1.09a
0.89ab
(kg/MT) 8
1.51 1.10a
0.94a SEM Probabilities 12
1.43 0.32 1.07a
0.95a 0.14 0.13
0.478 0.002
0.100
*Means in a row with the same letter superscript do not differ at P≤0.10 by Tukey’s test.
Table 2. Piglets performance and mortality Parameters
0 Number of weaned piglets
Piglets weight at weaning (kg)
Litter weight at weaning (kg) Litter BWG (kg)
Milk production (kg)* Mortality (%)
9.35c 5.99
56.01c 38.07c 152b 8.78c
4
9.67b 5.86
56.66c 39.42b 158a 5.74b
available, ie, offers high amounts of small chain polypeptides and free amino acids. These nutrients are readily available for absorption in the gut and metabolism utilization. Among these amino acids, there are high levels of glutamic acid (glutamine and glutamate), which provides a large amount of support to the gut (as amino acid and energy source) and also has excellent palatability, leading to an increase in feed intake. The nucleosides guanosine monophosphate (GMP) and inosine monophosphate (IMP) also contribute to improving the palatability. By stimulating the feed intake, there is consequently a better resistance to the challenges and also a higher BWG. The benefits found in supplementing the diets of piglets during
the nursery phase are a decrease in enteric problems, improvement in gut integrity (such as relationship villus height:crypt depth, mucosal thickness, and villus surface area), improvement in immune system responses (increase in levels of IgA) and subsequent improvements in performance (higher BWG). Hilyses®
improving health and passive immunity and milk quality in sows, and directly affecting the innate immune responses, decreasing pathogen contamination in the gut, providing nutrients with high digestibility and nucleotides.
References Available on request from
catharina.nieuwenhuizen@
barentz.nl
can be used as a strategy to help the piglets by
Hilyses®
(kg/MT) 8
10.20a 5.77
58.85a 40.36a 161a
5.12ab 12
10.23a 5.60
57.28b 39.80ab 159a 4.08a
1.04 5.93
1.01 0.58 5
1.30 0.072 0.1432
0.063 0.027 0.042 0.061
*Milk production estimated as 1 kg of milk = 4 kg of litter weight gain. ** Means in a row with the same letter superscript do not differ at P≤0.10 by Tukey’s test.
FEED COMPOUNDER SEPTEMBER/OCTOBER 2021 PAGE 37
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