ADVERTORIALS
TECHNOLOGY IN ACTION Springpacks Carbon Neutral Changes
You might recall the Carbon Neutral Pledge that Springpack announced in September 2021....
New TR4A range
supersedes earlier series with more efficient and accessible data monitoring
T&D Corporation, the Japanese market leader for wireless data loggers, presents the Bluetooth thermo recorder TR4A series, the successor to the TR4 series. Especially the model TR43A impresses with its external temperature and humidity sensor and offers completely new functionality in the TR4 series. Operating with Low Energy Bluetooth 4.2 and without pre-registration, loggers are immediately detected and automatically refreshed within the communication range of mobile devices such as smartphones and tablets.
T&D Corporation +49 6034 93 09 70
www.tandd.com
In short, Springpack wanted to make some changes to how they ran the business, making it even more environmentally friendly. They weren’t small changes either. They were big changes. And that’s just what they’ve done! Possibly the biggest change they have made to reduce their carbon emissions was launched in March 2022.
Following vital feedback from their customers, they simplified their delivery offer, moving to 2 delivery zones. Springpacks customers asked them to help them reduce their impact on the environment, and their new offering does just that. More orders are now being consolidated, with fewer deliveries being made to their regular customers.
The impact of this change was felt straight away, and the company will see the benefit when they analyse their carbon footprint for 2022.
Springpacks Carbon Neutral Changes – E-Cargo Bike Delivery Trial
In August 2022, Springpack wanted to reduce their Carbon Emissions even further, so they jumped on 2 wheels (well, 3 actually) to make some deliveries by bike! Working with Raleigh on this project, Springpack are currently trailing completing some local deliveries using one of their e-cargo bikes.
Keep your eyes peeled for the Springpack team riding around Worcester, and give them a wave if you see them!
SpringPack Ltd 01905 457 000
springpack.co.uk
How High Shear mixing can improve your Pharmaceutical Emulsions
In the pharmaceutical industry, emulsions are a key component in many formulations and products. Emulsions are used in the manufacture of pharmaceutical creams and lotions through to more complex applications such as adjuvants to improve the immune response to the antigens used in vaccinations. Whether it is a Water-In-Oil (W/O) emulsion or an Oil-In-Water (O/W) emulsion, getting the emulsion to remain stable in order to deliver the desired results - e.g. improved immune response - can be a challenging task. Whichever type of emulsion you are manufacturing, and for whichever product, the goal is the same: The globule size needs to be reduced sufficiently enough so that the oil and water phases are finely and uniformly dispersed into one another, ensuring that when the mixer is stopped, the phases remain combined and don’t begin to separate.
Some types of mixing equipment, such as stirrers and agitators, simply move the two phases around and don’t have any significant effect on the droplet size. So even though it may appear visually that the two phases have been combined, after time they will begin to separate. Separation of the emulsion is to be avoided as this can affect the shelf-stability, product quality and can even make products such as adjuvants unusable due to inconsistencies between batches. So while conventional mixing equipment like stirrers and agitators have their uses and are sufficient for simple blending tasks, a high degree of shear energy is required in order to obtain the finest possible droplet size. The more shear energy introduced into the mix, the smaller the droplets will become. As such, high shear rotor/stator mixers are advantageous for creating stable emulsions. Silverson high shear mixers can easily achieve emulsions with a globule size of 2 to 5 microns. Finer emulsions down to 0.5 microns can be obtained, depending on the formulation. This is achieved as follows:
the large globules from both phases are drawn by the high speed rotation of the rotor blades into the centre of the workhead. The globules are driven towards the workhead periphery by centrifugal force where they are subjected to a milling action in the narrow gap between the rotor blades and the inner wall of the stator. The globules are then subjected to additional high shear energy by being forced at high velocity through the stator perforations – in this case an emulsor screen, an interchangeable workhead which is available for all Silverson mixers. The smaller droplets are expelled radially from the workhead into the bulk of the emulsion, where the mixing cycle continues until the targeted droplet size and stability are achieved.
Silverson
sales@silverson.co.uk www.silverson.co.uk
58 SEPTEMBER 2022 | PROCESS & CONTROL
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