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TECHNOLOGY AND DATA MANAGEMENT N


ot only is the pharmaceutical industry starting to take notice of 


companies have also started to future- proof their approaches in order to keep    First, some background: one feature of the


ecosystem is the Thematic Scorecard, which evaluates companies on how equipped they are in a certain theme, such as AI, over the next two to three years. This is based on their AI activity and investment. Companies can garner a score between 1 and 5, with the score of 5 denoting a high AI commitment from the company. The score covers the use of AI for faster drug discovery and repurposing, enhanced clinical trial design, and smarter supply chains, among other uses. Of the pharma companies monitored, those with a score of 5 are AstraZeneca, Bayer, Bristol Myers Squibb, GSK, Johnson & Johnson (J&J), Novartis and Takeda Pharmaceutical.  pharma companies investing in AI in clinical trials. One is AstraZeneca working with Singapore-based Oncoshot regarding the latter’s AI-driven patient-to-trial matching technology. ConcertAI, meanwhile, has several collaborations with big pharma, such as one announced in 2021 with Janssen  aims to support trial designs, broaden new sites, and strengthen trial diversity. (J&J is the parent company of Janssen.)


AI in clinical trial patient matching While there has been increasing interest in AI in the pharma space, there are still untapped opportunities around using AI in clinical  with name recognition, such as DeepMind


“There has been increasing interest in AI in pharma. One of the clearer uses is applying the tech to match patients to a clinical trial”


38 | Outsourcing in Clinical Trials Handbook


 driven more by molecule optimisation, drug repurposing or drug discovery than by AI use in clinical development, says Lucas Glass, vice president of IQVIA’s Analytics Center of Excellence.


One of the clearer uses of AI in clinical trials is applying the technology to match patients to a clinical trial. Glass says there  sites sifting through their patient database to match patients with a given trial. The second is patients themselves looking for clinical trials that are best suited to them.  a relatively robust speed of development because the funding mechanisms in that space are clear, Glass explains. As for the second paradigm, in the US for


example, ClinicalTrials.gov can help patients  friendly, he says. A way to move the needle, he suggests, could be to have a bedside technology that alerts clinicians to patients of theirs who may be eligible for ongoing trials. Yet the development of such an approach  impact clinicians’ daily workflows, he notes. “I imagine it as a bit more of a passive thing, so it’s not like slamming it in the doctor’s face, but an alert on the side [of the screen] they can click on and see and explore.” Clinicians are likely to engage as they are used to doing their due diligence to explore all possible therapeutic options for their patients, he adds.


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