Antimicrobial resistance
backed by robust and accountable global AMR governance. Sustainable, consistent and diversified financing is essential to support the clear priorities and measurable targets for decisive action, while recognising local, national and regional contexts. “We must ensure universal access to
medicines, treatments, and diagnostics, while promoting preventive measures and investing in research, innovation, capacity building, and bold awareness initiatives. Our health depends on safe, nutritious food, and food security hinges on efficient, inclusive, resilient and sustainable agrifood systems. For nearly 80 years, FAO has been steadfast in its mission to secure safe, healthy foods for all. We fully support this declaration and remain committed to a collective action to eliminate AMR risks in agriculture and food systems,” said FAO Director-General QU Dongyu. “Evidence is mounting that the environment
plays a significant role in the development, spread and transmission of AMR, including transmission between humans, and animals to humans. And why if we’re to reduce the burden of AMR and its risks, the environment must be part of the solution. This declaration recognises this need, and UNEP will continue to be at the forefront of efforts to reduce the burden of AMR on societies and tackle the triple planetary crisis,” said Inger Andersen, Executive Director of UNEP.
Clear way forward The declaration formalises the standing Quadripartite Joint Secretariat on AMR as the central coordinating mechanism to support the global response to AMR. It also requests the Quadripartite organisations, together with countries, to update the Global Action Plan (GAP) on Antimicrobial Resistance by 2026 to ensure a robust and inclusive multisectoral response, through a One Health approach. The declaration also gives the Quadripartite the mandate to follow up and report back on implementation of the GAP and political declaration outcomes. It also acknowledges the critical contributions
of global AMR governance mechanisms, including the Global Leaders Group and the AMR Multi-Stakeholder Partnership Platform, committing to strengthening the latter, among others, to facilitate the multisectoral exchange of experiences, best practices, and the assessment of Member States’ progress in implementing multisectoral national action plans on AMR. The Quadripartite is taking on the declaration’s request for it to establish an independent panel for evidence for action against AMR in 2025, after a global consultation with countries. The panel will support countries in efforts to tackle AMR. The declaration emphasises key aspects,
including the importance of access to medicines, treatments and diagnostics, while calling for incentives and financing mechanisms
WHO’s 13 critical interventions
The WHO has previously outlined a core package of interventions to guide country prioritisation when developing, implementing and monitoring national action plans on AMR. These include: 1. AMR advocacy, governance and accountability in the human health sector in collaboration with other sectors.
2. AMR awareness-raising, education and behaviour change of health workers and communities.
3. National AMR surveillance network to generate good-quality data to inform patient care and action on AMR.
4. Surveillance of antimicrobial consumption and use (AMC/U) to guide patient care and action on AMR.
5. AMR research and innovation including behavioural and implementation science.
6. Universal access to WASH and waste management to mitigate AMR.
7. Implementation of IPC core components to mitigate AMR.
Priority actions include the need to: 8. Access to vaccines and expanded immunisation to manage AMR.
9. Health services for the prevention, diagnosis and management of infectious disease syndromes are available and affordable for all.
10. Supply of quality-assured, essential health products for the prevention, diagnosis and management of infectious disease syndromes.
11. Good-quality laboratory system and diagnostic stewardship to ensure clinical bacteriology and mycology testing.
12. Up-to-date evidence-based treatment guidelines and antimicrobial stewardship (AMS) programmes.
13. Implementation of regulations to restrict non-prescription antimicrobial sales.
Reference 1. Accessed at:
https://www.who.int/ publications/i/item/9789240082496
to drive multisectoral health research, innovation and development in addressing AMR. A stronger, transparent partnership between the public and private sectors, as well as academia is critical. The declaration also encourages countries
to report quality surveillance data on antimicrobial resistance and antimicrobial use by 2030, utilising existing global systems such as the Global Antimicrobial Resistance and Use Surveillance System (GLASS),12 the Global Database for Antimicrobial Use in Animals (ANIMUSE)13
of WOAH, and
the International FAO Antimicrobial Resistance Monitoring (InFARM).14
It further calls for
95% of countries to annually report on the implementation of their AMR national action plans through the Tracking AMR Country Self- assessment Survey (TrACSS).15
World AMR Awareness Week Ultimately, governments and the WHO have set out plans to tackle this existential threat, but everyone must play their part. The World AMR Awareness Week (WAAW) is a global campaign to raise awareness and understanding of AMR and promote best practices among One Health stakeholders to reduce the emergence and spread of drug-resistant infections. WAAW is celebrated from 18-24 November every year. The theme for the WAAW in 2024 is “Educate.
Advocate. Act now.” This theme was chosen based on feedback from an online survey among stakeholders from the human, animal, plant, and environmental health sectors, which collected nearly 200 responses globally. AMR is a pressing global health and
socioeconomic crisis. It has significant impacts on human and animal health, food production and the environment. Drug-resistant-pathogens pose a threat to everyone, everywhere. Yet, much more can be done to raise public and stakeholder awareness. This year’s theme calls on the global community
to educate stakeholders on AMR, advocate for bold commitments and take concrete actions in response to AMR. Stronger political leadership, advocacy and accountability are needed, at all levels, and the time to act is now.
To find out more about World AMR Awareness Week, visit:
https://www.who.int/campaigns/ world-amr-awareness-week/2024
References 1. Naghavi, Mohsen et al. Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050. The Lancet, Volume 404, Issue 10459, 1199 – 1226. Accessed at:
http://www.thelancet.
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