 the gut.


5.0 5.5 6.0 6.5 7.0


3.0 3.5 4.0 4.5


2.5 Control Presan-FY


Inorganic High (n=11) 1


22% increase in jejunum diversity by Selko Presan-FY


Inorganic Low


(n=11) 2


IntelliBond High (n=12) 3


IntelliBond Low


(n=12) 4


High IB increases alpha diversity in ileum P<0.05


decrease fat digestibility by deconjugating bile acids. This causes a decrease in lipid absorption and produces toxic me- tabolites that inhibit growth. Undigested protein bypassing the first part of the intestine can also serve as a food source for microbiota further down the intestinal tract. Toxic metabo lites produced during this fermentation process can impact intestinal cell turnover and hinder growth perfor- mance. Immature or damaged enterocytes are more vulnera- ble to coccidiosis. In addition, goblet cells may produce too much mucus, hindering feed passage rate and nutrient ab- sorption, resulting in a higher feed conversion ratio. A varied, stable microbial community is directly related to better feed conversion ratios in both healthy and challenged broilers. Greater diversity in microbial genera has been asso- ciated with greater resilience and better production perfor- mance in broilers. Specific bacteria also have distinct func- tions in the gastrointestinal tract. While the nutritional trace mineral requirements of broilers have long been known, researchers are studying how high levels of trace minerals affect mode of action in broilers, im- pacting performance as well as intestinal microbiota. Feeding a high concentration (125-225 ppm) of copper above nutri- tional levels has been shown to have strong antimicrobial ef- fects in broilers in regions where regulations permit higher levels of copper to be fed. However, the mineral source is crit- ical. Research suggests that crystalline structure of hydroxy copper and its strong covalent bonds, as in IntelliBond C, al- low more copper to reach the hind gut and support the stabi- lisation of microbiota. This unique mineral structure also pro- vides greater stability with sensitive feed ingredients, has more efficacy and supports better gut health and growth compared to sulphate and oxide sources. Studies have further shown that a synergistic approach helps to improve gut health, thereby supporting optimum animal performance without the use of antimicrobials. The ingredi- ents in Presan-FY, fed in conjunction with high levels of IntelliBond C, have been shown to reduce total microbial counts, increasing diversity in all segments of the gut (Fig- ure 2), while enahancing the strength and stability of microbi- ota in the entire gastrointestinal tract.


Equal performance results as AGP Four studies were conducted between 2017 and 2020 evalu- ating how the combination of Presan-FY and IntelliBond C impacts broiler growth performance and efficacy compared to AGPs. They all compared three treatment diets: a negative control with a standard commercial diet, a positive control which included BMD or Zinc Bacitracin at 50-55 ppm, and Presan-FY + IntelliBond C at high levels (125-225ppm). The studies were conducted in three different regions of the world, thereby covering different production systems, climate and housing conditions. The findings showed that broiler performance results equal to AGPs can be achieved with Presan-FY + IntelliBond C (Figure 3).


Consistent results The research shows that an integrated four-pronged strategy can support gut health. Feed formulation and dietary strate- gies which include the synergistic use of feed additives can help to improve gastrointestinal development and digestion, the absorption of nutrients and immunity. Controlled re- search has consistently shown that Presan-FY + IntelliBond C is an effective combination to improve broiler performance while reducing antimicrobials.


Figure 3 - Relative broiler performance in four independent studies of Presan-FY + IntelliBond C compared to AGP (horizontal line indicates AGP performance results). Growth perf: PC vs PFY + IBC


110.00 -0.2% 100.00 -0.4% -0.1% -0.2%


90.00


80.00


70.00


60.00


50.00 Final BW ADG ADFI FCR


▶ POULTRY WORLD | No. 7, 2020


29


Trial 1 Trial 2 Trial 3 Trial 4


Faith_PD


Trial 1 Trial 2 Trial 3 Trial 4


Trial 1 Trial 2 Trial 3 Trial 4


Trial 1 Trial 2 Trial 3 Trial 4


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