GUT HEAL ▶▶▶TH
Synergistic feed additive: A strategy to reduce antimicrobials
Gut health is an enduring challenge for broiler producers, accounting for up to 80% of antimicrobials used in poultry production, given that most other health issues can be prevented by vaccines. Essential to ensuring optimum absorption of nutrients in the bird, gut health is a key factor in supporting immunity.
BY YVONNE VAN DER HORST, NARENDRA VENKATAREDDY AND BARBARA BRUTSAERT, TROUW NUTRITION
A
s most of a broiler’s immune cells reside in the gut in the form of GALT (gut associated lymphoid tissue), maintaining a healthy gut is critical to sup- porting broiler health. Research shows that an inte-
grated four-pronged strategy (Figure 1) leveraging the rela- tionship between nutrition and microbiology, immunology and physiology can help to improve and maintain gut health while reducing the use of antimicrobials. Combined with sound feed and farm management, a health management programme will help producers consistently achieve success- ful flocks while reducing the need for antimicrobials. In addi- tion, the vaccination programme should be carefully custom- ised and applied correctly, with antibiotics used responsibly: as little as possible and as much as needed, based on antibio- grams. A synergistic approach leverages different feed addi- tives as part of a four-pronged gut health strategy to support broiler health while reducing or removing antibiotics. As a first step, special blends of organic acids can reduce the pH in the crop and proventriculus to levels where many pathogenic bac- teria struggle to survive, while also supporting digestion. Next, specially-developed feed additives can strengthen the gut
Figure 1 - Four pillars help support gut health.
barrier function and balance the microbiota. Finally, specific in- gredients can help immunemodulation, directly and by con- tributing to a healthier gastrointestinal tract.
Synergistic combination explained Supplementing feed with Selko Presan-FY and Selko Intelli Bond C is a proven and promising synergistic approach to an AGP-free production system. Presan-FY and IntelliBond C focus on two aspects of gut health: strengthening the gut barrier function and microbiota stabilisation, while improving gut digestion and immune modulation to achieve notable health and performance benefits. A well-modulated gut sup- ports a bird’s immune response when necessary, without trig- gering an immune system overreaction.
Prevent bacterial intake & Support digestion
Strengthen gut barrier function
Stabilization of microbiota
Managing multiple and complex challenges The physiology of broiler gut integrity, its microbial commu- nity and immune systems, is complex and highly interactive. Enterocytes in the gut wall are connected through complex protein structures called tight junctions which maintain the barrier between intestinal cells. These tight junctions control which substances are allowed to translocate through the bar- rier, keeping valuable proteins on the correct sides of the cell wall for essential cell functions to occur. The ingredients for Presan-FY are carefully selected to support the gut wall barri- er. Presan-FY is a synergistic blend of phenolic compound, slow release C12, target release butyrates, medium-chain fat- ty acids (MCFA) and organic acids. Presan-FY supports the gut wall barrier and reduces total bacterial counts in the intestine, while supporting a varied and stable microbiota. Microbial activity affects growth and efficiency as microbes inside the gut compete with the host for nutrients. A reduc- tion in microbial activity in the intestine is the main suggest- ed physiological process used to ex- plain the effects of antibiotic growth promoters (AGPs) in improving ani- mal performance. Higher concentra- tions of intestinal microbes also
Th1 Th2
Support natural defence system
28 ▶ POULTRY WORLD | No. 7, 2020
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