ANALYTICAL & LABORATORY EQUIPMENT


The inside story on how a new testing facility enables small manufacturers and start-ups to put cytocentric principles to the test


he RegeneratOR Test Bed is an exciting game-changer. Te testing facility, located in North Carolina, USA, provides supportive technology


LAB SPACE T


LEADING-EDGE


at no cost, allowing companies to test and prove their cell-based products at various stages of development. Te Test Bed uses cytocentric principles, an innovative philosophy of putting the needs of the vulnerable cells front and centre while growing and manipulating them in vitro. Cytocentric cell manufacturing keeps the critical cell process parameters of temperature, CO2


, and O2 8 www.scientistlive.com at optimum


physiologic levels over the entire production process, not just during incubation steps. By eliminating the fluctuations and suboptimal transients caused by all the typical exposures to air, cytocentric manufacturing produces better cells and more consistent results. Any or all critical quality attributes can be improved, sometimes dramatically. “Cells are very important to the whole


process of regenerative medicine,” explains Dr Anthony Atala, MD, director of the Wake Forest Institute for Regenerative Medicine (WFIRM). “When you


regenerate tissues and organs, you are dealing with two major ingredients: the most important are the cells that make up the functional component of the tissue and the many biomaterials we may use.” Te RegeneratOR Test Bed is


supported by the collaborative efforts of WFIRM, the largest regenerative medicine institute in the world, and the RegenMed Development Organisation (ReMDO), a non-profit headquartered in Winston-Salem, North Carolina, with a mission to accelerate the discovery and translation of regenerative medicine


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