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Studies and research have shown that approximately 340 mg of rhodiola that is standardized for both rosavin and salidro- side, taken in divided doses in the morning and afternoon, can be used effectively and safely, without side effects.


Resveratrol


According to numerous studies, resvera- trol, found in grape skins, peanuts, blueber- ries, and cranberries, improves quality of life by slowing age-related deterioration and functional decline.


A 2008 published study in mice, con-


ducted and supported in part by the National Institute of Aging of the NIH, confirms that this compound mimics some of the effects of calorie restriction, the most effective way found to date to alleviate age-associated dis- ease in mammals. The study also found that resveratrol promoted cardiovascular health, significantly lowered cholesterol, improved bone health, and enhanced balance and mo- tor coordination, in the lab subjects.


Curcumin


Studies have shown that curcumin, a potent antioxidant from turmeric, combats not only inflammation and oxidative stress at the cellular level, two main causes of aging, but also bacteria (including H. pylori), fun- gus/yeast, and viruses. It thus targets a wide range of diseases, including rheumatoid ar- thritis and osteoarthritis, diabetes, cardiovas- cular disease, Alzheimer’s disease, inflam- matory bowel disease, and cancer, including tumors and breast and cervical cancers. Curcumin safely combats inflamma- tion principally by inhibiting the cytokine NF-kappaB, which acts like a switch to turn on the genes that produce the body’s inflammatory responses. Gene expression of NF-kappaB increases in aging adults, thus causing numerous degenerative diseases and those related to compromised immunity. Curcumin also reduces inflammation by inhibiting other cytokines and COX-2 and 5-LOX activity.


Human clinical studies have shown that


a patented curcumin formulation (BCM-95) greatly enhances the bioavailability of this nutrient, which is generally difficult to ab- sorb. This form delivers up to 7 times better absorption than ordinary 95% standardized curcumin and remains in the bloodstream for 8-12 hours, almost twice as long as conventional supplements. Caution: at high doses, curcumin can cause diarrhea and mild nausea in those with sensitive digestive systems.


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