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Bayer Releases Study Results on Zelnate®
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B
AYER ANIMAL HEALTH RELEASED THE RESULTS OF ITS EXAMI- nation on how Zelnate DNA Immunostimulant may
improve health and performance outcomes when used in a beef cattle herd health on-arrival program, and to ob- serve the potential benefi ts of delaying the modifi ed-live vaccine (MLV) until after initial stress and Mannheimia haemolytica challenges are experienced. The key study results were:
• At the conclusion of the study, Zelnate signifi cantly reduced overall mortality at every measured time frame (60 days, 116 days and close- out), regardless of whether the MLV vaccine was administered on ar- rival or MLV delayed 30 days.
• Zelnate signifi cantly reduced bovine respiratory disease (BRD) mor- tality at 60 days (with a 30.2 percent reduction in total mortality and a 28.4 percent reduction in BRD mortality) and 116 days (with a 31.5 percent reduction in total mortality and a 27.5 percent reduction in BRD mortality) compared to calves not treated with Zelnate. Zelnate followed the same trend at close-out.
• Although not statistically signifi cant, Zelnate showed a trend in reduc- ing the BRD case fatality rate throughout the study.
• Delaying the MLV signifi cantly reduced second BRD treatments at all three time frames, and signifi cantly reduced BRD re-treatment risk at 116 days and close-out. “Because BRD remains such a challenge in the cattle industry, Bayer
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is focused on fi nding new and innovative ways to attack this devastating disease,” says Jim Sears, senior technical services veterinarian, Bayer Ani- mal Health. “That includes looking at how recently developed products, such as Zelnate, can be used in different ways and at different stages in a producer’s BRD prevention and treatment protocol.” The study included a total of 5,179 crossbred heifer calves at a commer-
cial feedlot in southwest Kansas and looked at whether multiple biologicals in the arrival processing of medium to high risk cattle in a feedyard may be causing undue levels of stress and compromising the immune system. The primary BRD challenges faced by such cattle in the early stages of their feeding period are usually associated primarily with or caused di- rectly by Mannheimia haemolytica infections. “Overall, we saw an added value of including Zelnate in processing
cattle, with Zelnate consistently improving survivability, resulting in a 22 percent reduction in overall death loss, regardless of on arrival or delayed processing,” says Sears. “These study results remain consistent with prior studies in demon-
PORTABLE & STATIONARY SYSTEMS 46 The Cattleman December 2016
strating how Zelnate reduces mortality in cattle herds.” For more information or to obtain a copy of the report, call Bayer Vet- erinary Services at 800-422-9874 or visit
Zelnate.com.
thecattlemanmagazine.com
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