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historical height loss ≥ 4cm; self-reported, but undocumented prior vertebral fracture and glucocorticoid therapy equivalent to ≥5mg prednisolone for ≥ three months51


. In practice, adding VFA to a service and


scanning those at risk of vertebral fracture can improve targeting of treatment, with a modifiable underlying cause being found in 21% of those diagnosed with vertebral fracture26


. Since the presence of a prevalent


vertebral fracture is highly predictive of incident fractures, treatment decisions will be influenced by the identification of a vertebral fracture60-62


. However, VFA may not be required in patients with documented vertebral fractures unless a change in treatment decision depends on identification of an incident fracture62


Conclusion The use of VFA enhances DXA services, provides better identification of those who require treatment for fragility fractures and offers additional tools for cases where DXA struggles to achieve an accurate bone measurement. However, VFA is not indicated in all patients attending the service and should be targeted at those for whom epidemiological data demonstrate a heightened risk for vertebral fracture. In this group of patients, the additional costs and burden to the service are outweighed by the overwhelming benefits achieved by the diagnosis of a vertebral fracture. It is therefore an important addition for consideration in DXA services where it is not currently offered.


References 1.


Leali PT 2. 3. 5. 6. , Muresu F , Melis A et al. Skeletal fragility definition. Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases. 2011; 8(2): 11-3.


Ensrud KE, Thompson DE, Cauley JA et al. Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass. Fracture Intervention T 2000; 48(3): 241-9.


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Baim S. Assessment of Fracture Risk. Rheum Dis Clin North Am. 2011; 37(3): 453-70. an Staa TP


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Blake GM, Fogelman I. The role of DXA bone density scans in the diagnosis and treatment of osteoporosis. Postgrad Med J. 2007; 83(982): 509-17.


Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. World Health Organization technical report series 1994; 843: 1-129.


7. Garg MK, Kharb S. Dual energy X density


8. Hillier T -ray absorptiometry: Pitfalls in measurement and interpretation of bone mineral . Indian Journal of Endocrinology and Metabolism 2013; 17(2): 203-10.


A, Cauley JA, Rizzo JH, et al. WHO Absolute Fracture Risk Models (FRAX): Do clinical risk factors improve fracture prediction in older women without osteoporosis? Journal of Bone and Mineral Research. 2011; 26(8): 1774-82.


9. K M Knapp JLGG, N Peel. Dual energy x-ray absorptiometry: artifacts and pitfalls in interpretation. Osteoporosis Review


. 2014; 22(1): 10-6.


10. El Maghraoui A, Roux C. DXA scanning in clinical practice. Qjm-an International Journal of Medicine. 2008; 101(8): 605-17.


11. Bandeira F , Cusano NE, Silva BC, et al. Bone disease in primary hyperparathyroidism. Arquivos Brasileiros de Endocrinologia e Metabologia. 2014; 58(5): 553-61. 12. Carnevale V , Romagnoli E, D'Erasmo L et al. Bone damage in type 2 diabetes mellitus. Nutrition, Metabolism, and Cardiovascular Diseases: NMCD. 2014; 24(11) 1151-7. -51- , Dennison EM, Leufkens HGM et al. Epidemiology of fractures in England and Wales. Bone 2001; 29(6): . .


One in twelve men and one in six women will suffer a symptomatic vertebral fracture during their lifetime


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