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GENETIC predisposition


ENVIRONMENTAL influences


MICROBIAL interactions


GEM


The Crohn’s and Colitis Canada Inflammatory Bowel Disease GEM Project is a major, multi-centre clinical research study investigating how genetic predisposition, environmental influences and microbial influences combine to trigger the development of Crohn’s disease. This study could hold the key to unlocking the mystery of IBD.


In April 2014, Crohn’s and Colitis Canada and the Leona M. and Harry B. Helmsley Charitable Trust announced the largest-ever funding commitment to Crohn’s disease research in Canada. The $10 million funding commitment is made possible by a lead gift of $6 million from the Helmsley Charitable Trust, one of the largest family trusts in the United States, which includes a focus on Crohn’s disease amongst its funding priorities. The Helmsley Charitable Trust grant will be matched by a further $4 million in active fundraising from Crohn’s and Colitis Canada, Mount Sinai Hospital, and University of Toronto.


“We saw the value of the GEM Project immediately,” said Jim O’Sullivan, Program Director of the Helmsley Charitable Trust’s IBD & Crohn’s Disease Program. “We are confident that our grant will be an accelerator for this research and help to provide answers sooner for people living with Crohn’s and their families.”


Dr. Ken Mount Sinai GEM II $ 2,888,184 Croitoru Hospital


Project Year 1 of 4


RESEARCH REPORT 2014 | 12


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