| HAIR GROWTH | PEER-REVIEW
was conducted with 26 volunteers with thin hair who received five local treatments — half with PRP plus
delteparine and half with PRP alone — and evaluated for a period of 12 weeks (Figure 2). Experimental and control areas were photographed, digitally measured and biopsies taken for histology examination. Significant differences were seen in hair cross-sections, but not in hair density. The interesting point for the purposes of the present article is that PRP improved density by 16% at 12 weeks. Greco and Brandt17
found that traumatising and
infusing growth factors into the scalp reversed miniaturisation over an 8-month period when compared with control. Ten hair samples were taken from each patient; five patients in the Control Group (CG) and five from the Treatment Group (TG). Hair diameter was measured using a Starrett micrometer. In the TG , 60 cc of blood was drawn and 10 cc PRP was processed. The CG also had 60 cc of blood drawn, but this was not processed. The scalp was first traumatised in both groups with a 1 mm microneedling roller to initiate keratinocyte migration and wound healing. The TG was then injected with PRP. Normal saline was injected into the scalps of the CG in a similar fashion. Patients were evaluated and hair diameter measurements were taken using the micrometre at 4 months and 8 months post-treatment.
The CG demonstrated a 2.8% average decrease in hair
shaft diameter at 4 months and 3.5% decrease at 8 months (this is the classical evolution of androgenic alopecia). An increase of 9.7% in average hair shaft diameter at 4 months and then 6.1% at 8 months in the TG was very significant (Figures 3 and 4). For the authors’ coming
Figure 5 (A) Before and (B) 3 months after one session of platelet-rich plasma treatment
Greco and Brand
evaluation, minimal guidelines should be respected. The number of inclusion must be sufficient (more than 50), digital measurement must be proceeded with a tattoo mark (to be at exactly the same place), short cut and dyeing solution if necessary. The following parameters must also be determined: hair density, caliber and ratio (anagen : telogen). Photography must also be standardised. In the author’s study, 60 patients (male and female) were included, who all received digital measurements (tattoo mark, hair density, caliber and ratio) and had standardised photographs taken. As with the Greco and Brandt study17
, 60 cc of blood was drawn
and 10 cc of PRP processed using the MyCells kit. The scalp was first traumatised with a 1.5 mm microneedling roller. Patients underwent two treatment sessions at
Figure 6 (A) Before and (B) 9 months after two platelet-rich plasma sessions
found that traumatising and infusing growth factors into the scalp reversed miniaturisation over an 8-month period when compared with control.
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