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PEER-REVIEW | HAIR GROWTH |


PLATELET-RICH PLASMA:


A THERAPY FOR HAIR GROWTH


Gilbert Amgar and Pierre Bouhanna investigate the


novel application of platelet-rich plasma preparations as a treatment for male and female hair-loss


ABSTRACT Medical treatments for hair-loss, such as minoxidil lotion, finasteride 1 mg oral, or cyproterone acetate oral, may impede the development of baldness. In recent years, however, it has also been found that platelet-rich plasma (PRP) can also be injected into the scalp to reverse hair miniaturisation. This article will explore three main points: how growth factors interfere with the hair cycle, a review of the literature pertaining to treatments for hair loss (particularly the use of PRP), and a proposal of guidelines for future treatment evaluations.


male and female pattern baldness as a result of changes in its metabolism. In normal hair loss, less than 100 hairs fall each day


I


GILBERT AMGAR is Aesthetic Practitioner, France, and PIERRE BOUHANNA is Dermatologist and Expert in Hair Surgery, Paris, France.


email: gilbert.amgar@orange.fr 20 ❚


KEYWORDS PRP, hair growth, growth factors, phototrichogram, androgenic alopecia, alopecia areata


June 2013 | prime-journal.com


and are replaced by new, thick hair. In the evolution of male and female pattern baldness, the new hair is fine and thin (intermediate hair or miniaturised hair). Male and female baldness usually progresses in a definitive pattern. Medical treatments for hair loss, such as minoxidil lotion, finasteride 1 mg oral, or cyproterone acetate oral, may impede the development of baldness. In recent years, however, it has also been found that platelet-rich plasma (PRP) can also be injected into the scalp to reverse hair miniaturisation. A phototrichogram using a digital camera enables an objective measurement of hair-growth parameters2


, such as


density, number of miniaturised and/or terminal hairs, and hair growth rate on a selected and tattooed area (Figure 1).


NTEREST IN THE REVERSAL OF BALDNESS has been enhanced by a precise multifactorial classification of each individual to effectively reverse male and female androgenic alopecia (AGA) in selected patients1


. Dihydrotestosterone (DHT) is the specific hormone responsible for


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