Contents
DDW the quarterly business review of drug discovery & development
Publisher and Editor-in-Chief Robert Jordan
Robert@rjcoms.com
Consultant Editor Dr Roger Brimblecombe
Contributing Author Dr John Comley
Publishing Manager Damian Doherty
Damian@rjcoms.com
Design & Production Melissa Chadderton
melissa@rhubarbcreative.demon.co.uk
Circulation & Production Controller Charles Davenport
CD@rjcoms.com
Editorial Advisors Dr Steve Arlington Dr Nigel Brown Dr David Clough Dr Gregory Lennon Dr Keith Mansford Professor Stephen Naylor Dr George Poste Dr Amber Salzman Dr David U’Prichard Dr Timothy Wells Dr Rene Ziegler
Drug Discovery World (USPS 018-892) is published four times a year by RJ Communications & Media Ltd, 39 Vineyard Path, London SW14 8ET, United Kingdom. Tel: +44 (0)20 8487 5656 Fax: +44 (0)20 8487 5666 E-mail:
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© 2010 RJ Communications & Media Ltd All rights reserved. ISSN 1469-4344
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Front cover illustration courtesy of G. Brad Lewis/Science Photo Library Drug Discovery World Summer 2010 5
dr ug discov er y wo r l d contents
VOLUME 11 ISSUE 3 ● SUMMER 2010 Introduction
Dr Roger Brimblecombe Consultant Editor
Therapeutics New Trends and Therapeutic Approaches for the Management of Diabetic Retinopathy Dr Didier Pruneau
Biomarkers
Biomarkers Make Their Mark on Current Research and Drug Development Trends
Stéphane Parent and Dr Gregory Cosentino
Cell Culture 3D Cell Culture – Easier Said Than Done! Dr John Comley
Informatics
Enterprise ELNs as a Foundation for Preclinical Drug Development Simon Beaulah, Dr Paul Denny-Gouldson and Dr Scott Weiss
Assays Tracking HTS Assay Development Time – Opportunity for Developing Drug Discovery
Dr Jennifer Hartigan, Cindy Liu and William Downey Molecular Diagnostics
Overview of Companion Diagnostics in the Pharmaceutical Industry –Part II: Business Models Dr Stephen Naylor and Toby Cole
Assays
Fluorescence Lifetime – Finally Picking up Momentum! Dr John Comley
Personalised Medicine
Personalised Medicine – Market and Regulatory Landscape Dr Enal Razvi and Dr Patricia Hurley
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