36 prOCESSIng tECHnOLOgy
Streamlined, flexible operations
demanded for control strategies
G
enetic disease specialist Shire product line, Experion Batch Manager. Introduced
As two major new
Human Genetic Therapies (HGT) in 2008, Experion Batch Manager further
bio-investments show,
is investing US$250m in a new simplifies operations by allowing manufacturers
the need for streamlined,
production facility at Lexington, to quickly execute complex batch recipes reliably
flexible manufacturing Massachusetts, USA. The facility is scheduled for in a regulated environment.
is driving investment completion in spring 2010 and when complete Additionally, the OneWireless mesh network
in the latest control
will be the largest disposable biotechnology site technology will allow Shire to mount controllers
technologies. Sean
in the country. on moveable equipment without having to worry
Ottewell explains.
This is a new concept where disposable about cabling issues, which can help increase
vessels and tank liners are used to reduce the cost their production flexibility, safety and efficiency.
Comme le montrent deux
of cleaning and verification of process equipment. Also, wireless remote operator stations will be
nouveaux investissements
The site also will include cell-culture production, used to help reduce the overall number of stations
majeurs dans le domaine
a clinical suite, and just-in-time warehousing. required and eliminate the need for expensive
des biotechnologies, le “Technology that simplifies scale-up from hardened enclosures in environmentally sensitive
besoin d’une fabrication
R&D to commercialised production is critical for areas.
rationalisée et souple
biotech facilities to produce as efficiently and For its part, PHD will pull information from
oriente l’investissement
reliably as possible,” explained
vers les technologies de
Don Wuchterl, director of
contrôle les plus récentes.
Les explications de Sean
manufacturing with Shire HGT.
Ottewell.
In order to control
manufacturing processes at the
new facility, Shire HGT has selected
Wie zwei umfangreiche a number of Honeywell solutions,
neue Investitionen in die
including Experion Process
Biotechnologie belegen,
Knowledge System (PKS), Experion
werden Investitionen in
Batch Manager, the OneWireless
neueste Kontrollverfahren
von der Forderung nach
industrial wireless network and
einer optimierten und
Uniformance Process Historian
flexiblen Herstellung
Database (PHD).
motiviert. Ein Bericht von
“Experion and OneWireless are
Sean Ottewell. proven to streamline operations
and will provide the flexibility
required for a multi-purpose
facility such as ours,” added
Wuchterl.
Shire will use Experion as the
primary control platform for the
new facility. The system helps
operators run production by
integrating critical subsystems
throughout the plant, providing a
single view into the manufacturing
process via Experion client
operator stations. The processing
capacity of the C300 controller will
reduce the amount of hardware
needed to automate Shire’s
manufacturing process, as well as
reduce operating costs.
Shire will also use one of the Fig. 1. Operations management software will be used to boost
newest additions to the Experion cell culture capabilities at the new facility.
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