SPONSORED: FLOW CYTOMETRY AND MICROSCOPY VersaLase system
imaging, which gives a highly accurate image of a cell, without the need for extremely expensive microscopy systems. Many laboratories have built their own systems with much lower cost setups, with very high success.’ Vortran Laser Technology’s
tech is used in many laboratories around the world, including the Nico Laser system. Throne said: ‘Dr Kurt Thorn, formerly the manager of the Nikon Imaging Center at the University of California San Francisco [UCSF], built his own light sheet setup with our Stradus VersaLase multi- wavelength laser systems. ‘Also, Nico Stuurman has used our systems for many of his setups at UCSF for various
imaging platforms, including as an input to his Yokogawa Spinning Disk setup.’ But there are still a number of engineering challenges to address in confocal microscopy and flow cytometry. Throne explained: ‘Typically, it is the variation in the beam quality and instability of the beams from standard laser diode modules. ‘There are a number of optical engineering hurdles to overcome, along with the drive electronics. On top of that, there are many other engineering nuances, such as ensuring polarisation stability and thermal stability that are key to our product designs.’ Vortran Laser Technology employs several engineering
principles to address these issues. Throne said: ‘First, are the decades of experience in designing the electronics to ensure the diode output is stable and low noise. Second, are the proprietary mechanical solutions that reduce stress on the optics and ensure alignment of the beam, eliminating any optical aberrations or negative influences from the beam shaping optics.’ In its most recent white
paper, the company explains how its laser diode systems are providing the reliability to allow researchers to concentrate on their work in numerous fields, instead of worrying about constantly servicing or adjusting their setup. Throne explained: ‘The most
impressive result is that we have yet to have a blue (375 to 514nm) laser diode fail in the field. With more than 4,000 units deployed of these wavelengths, no laser diode has had a failure for any parameter we specify.
‘This is especially impressive when looking at the near-
UV wavelengths with their susceptibility to contamination and degradation over time. This is mainly due to our patented Sealed Optical Cavity which protects all of the critical optics from environmental conditions. Many of these units in the field have well over 50,000 hours of continuous operation without issue.’ Vortran Laser Technology
is now focusing on reducing costs, while continuing to increase the reliability of its laser solutions. Throne concluded: ‘Going
forward we see all systems requiring a higher performance at an economical value. Every industry is seeing pressure for both performance and reliability, and we intend to lead that charge with lasers that have unprecedented reliability. ‘Especially in microscopy,
there will be more requirements to integrate light sources with less technical requirement and more flexibility, allowing end users to service multiple imaging platforms with a single source.’ EO
New White Paper now online
By Vortran and Frankfurt Laser
VIEW FOR FREE*
How Vortran laser technology reduces lead times and increases stability for laser diode systems
www.electrooptics.com/white-papers Vortran
Electro Optics
Vortran
*Registration required
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