Cancer research to benefit from 100 million frames per second camera News
Te Rosalind Franklin Institute (RFI), based in Oxfordshire, UK, is building the world’s most advanced high-speed video camera for imaging tissue in cancer research. Te camera will be able to capture
up to 100 million frames per second at 1 megapixel resolution, operating across a wide optical spectrum, from ultraviolet to infrared. It will be used to further
researchers’ understanding of a new cancer drug delivery method using ultrasound. By imaging at such high frame rates researchers will see how ultrasound interacts with drug-loaded particles and tissue, and how that enables controlled uptake of drugs into cancer cells, helping researchers understand the biophysical mechanisms behind the drug delivery method. Te new instrument will be
developed through a collaboration between an academic team at the University of Oxford and a UK SME specialising in high-speed imaging, Invisible Vision. Once completed, it will be housed at the new Rosalind Franklin Institute (RFI) being built at the Harwell Research Complex in Oxfordshire for use by researchers in the UK and the rest of the world. Chemotherapy is one of the most
common treatments for cancer, using powerful drugs to kill cancer cells or stop them from growing and spreading to other parts of the body. Tese drugs are introduced into the bloodstream and absorbed into the surrounding tissue. Professor Eleanor Stride, from
the University of Oxford, explained: ‘A major challenge with current delivery methods is that they rely on the active molecules reaching and entering the tumour cells by diffusion. Tis makes it difficult to ensure that all parts of a tumour are treated and leads to terrible side effects because large volumes of healthy tissue also absorb the drug. We need to find a better way to get these drugs into cancer cells specifically, quickly and effectively.’
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www.baumer.com/cameras/LXT VT-35_LXT_140x195_IMVE_180514.indd 1 14.05.18 11:51 August/September 2018 • Imaging and Machine Vision Europe 7 She continued: ‘Te approach
introduces harmless particles into the bloodstream and then uses ultrasound to activate them, releasing the drug at a specific site and driving it into the tumour’s [cancer cells]’. Te new instrument will be a key
part of the core capability of the RFI’s Insight laboratory, which will be devoted to developing technology for imaging and therapy at the intersection of light and sound. Professor Stride added: ‘Most current devices are limited to the
optical part of the spectrum or look at specific wavelengths. Tis camera will look at the full spectrum, from ultraviolet to infrared. It will help us see how ultrasound affects the particles and how exactly it helps improve the drug delivery.’
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