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Informatics


Figure 1 Costs of drug development have risen while overall probability of regulatory approval has reduced1. Image taken from DiMasi JA et al. J Health Econ. 2016;47:20-33


success in the drug development arena. These tech- nologies have significantly increased the speed and breadth of research processes that may be imple- mented, generating an exponentially expanding volume of data. Figure 2 shows the growth in genome sequencing data generation alone5. However, security and confidentiality issues associ- ated with data access have led to further challenges and complexity, obstructing efficient use of this information and impeding drug development.


There is a growing need for data-driven solu-


tions that support drug development, research and clinical trials, while ensuring that security require- ments are appropriately met. Additional regulatory challenges in these fields have also arisen at a time when achieving significant competitive advantage depends heavily on effective data aggregation. For example, collection and aggregation of electronic health records or clinical genomics information, alongside research data, may support identification


Figure 2 Growth of genome sequencing data5. Image taken from Stephens ZD et al. PLoS Biol. 2015 7;13(7):e1002195


Drug Discovery World Summer 2018


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