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Microfluidics


References 1 Seah et al. Microfluidic single-cell technology in immunology and antibody screening. Mol Aspects Med. 2018;59:47-61. 2 Chokkalingam et al. Probing cellular heterogeneity in cytokine-secreting immune cells using droplet-based microfluidics. Lab Chip. 2013;13(24):4740-4744. 3Yuan et al. Challenges and emerging directions in single-cell analysis. Genome Biology. 2017;18:84. 4 Proserpio et al. Single-cell technologies are revolutionizing the approach to rare cells. Immunol Cell Biol. 2016;94(3):225-229. 5Yeo et al. Microfluidic enrichment for the single cell analysis of circulating tumor cells. Sci Rep. 2016;29(6):22076. 6 Regev et al. The Human Cell Atlas: from vision to reality. Nature. 2017;550:451-453. 7 Liu et al. The history of monoclonal antibody development – Progress, remaining challenges and future innovations. Annals of Medicine and Surgery.2014;3:113-116. 8 Ecker et al. The therapeutic monoclonal antibody market. MAbs. 2015;7(1):9-14. 9 Shalek et al. Single-cell analyses to tailor treatments. Sci Transl Med. 2017;9(408). 10 Editorial. What happened to personalized medicine? Nat Biotechnol. 2012;30(1):1. 11 Borsu et al. Clinical Application of Picodroplet Digital PCR Technology for Rapid Detection of EGFR T790M in Next-Generation Sequencing Libraries and DNA from Limited Tumor Samples. J Mol Diagn. 2016;18(6):903- 911. 12Watanabe et al. Multiplex Ultrasensitive Genotyping of Patients with Non-Small Cell Lung Cancer for Epidermal Growth Factor Receptor (EGFR) Mutations by Means of Picodroplet Digital PCR. EBioMedicine. 2017;21:86-93. 13 Gross et al. Technologies for Single-Cell Isolation. Int. J. Mol. Sci. 2015;16:16897-16919. 14Whitesides. The origins and the future of microfluidics. Nature. 2006;442(7101):368-373. 15 Smith et al. Sensitive, high throughput detection of proteins in individual, surfactant- stabilized picoliter droplets using nanoelectrospray ionization mass spectrometry. Anal Chem. 2013;85(8):3812-3816. 16 Liu et al. High-throughput screening of antibiotic-resistant bacteria in picodroplets. Lab Chip. 2016;16(9):1636-1643. 17 El Debs et al. Functional single-cell hybridoma screening using droplet-based microfluidics. Proc Natl Acad Sci USA. 2012;109(29):11570-11575. 18Theberge et al. Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology. Angew Chem Int Ed Engl. 2010;49(34):5846-5868. 19 Chin et al. Microfluidics-based diagnostics of infectious diseases in the developing world. Nat Med. 2011 Jul 31;17(8):1015-1019.


20 Pandey et al. Microfluidics Based Point-of- Care Diagnostics. Biotechnol J. 2018;13(1). 21 Han et al. CRISPR-Cas9 delivery to hard-to- transfect cells via membrane deformation. Sci Adv. 2015;1(7):e1500454. 22 van Duinen et al. Microfluidic 3D cell culture: from tools to tissue models. Curr Opin Biotechnol. 2015;35:118-126. 23 Inamdar et al. Microfluidic cell culture models for tissue engineering. Curr Opin Biotechnol. 2011;22(5):681-689. 24 Luni et al. High-efficiency cellular reprogramming with microfluidics. Nat Methods. 2016;13(5):446-452. 25 Simon et al. in Day et al (eds). Microdroplet Technology: Principles and Emerging Applications in Biology and Chemistry, Integrated Analytical Systems. Springer Science+Business Media. 2012. 26 Schoeman et al. Electrofusion of single cells in picoliter droplets. Sci Rep. 2017;8(1):3714. 27 Hammond et al. Picodroplet partitioned whole genome amplification of low biomass samples preserves genomic diversity for metagenomic analysis. Microbiome. 2016 Oct 6;4(1):52.


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Drug Discovery World Summer 2018


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