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Sample Management


have a multitude of shapes depending on size con- straints. On the other hand, the software offering is a user-friendly database that can work as a Sample Data Management web application for end-users or can also be accessed through Web API for a full LIMS integration into partner products. Bluechiip technical support offers engineering and aftersales support for all customers (Figure 13).


In today’s biomedical research environment, biobanks are a repository for the physical sample, but increasingly also for the exponential amount of data tied to each sample. Further, the type and amount of data is multiplying and the information desired by researchers is becoming more broad and complex. As a result, many research organisations are seeking technologies and strategic processes to improve overall sample intelligence and increase the global visibility and quality of the samples within their distributed biobanks. In response, Brooks Life Sciences (www.brooks.com/life- science) recently launched its BioStudies® Biobank Data Management System. Designed specifically to integrate sample inventory and other data related to samples from disparate data sources, BioStudies connects sample inventory, consent, phenotypic and clinical data, giving researchers a single tool to support an integrated quality approach to optimise the availability of sample collections within popu- lation and research-based studies. Leveraging its ISIDOR™ platform, BioStudies provides advanced data visualisation that enables research organisa- tions to elevate sample data from a commodity view into a more strategic, reusable and ultimately valuable scientific asset. The insight and analytics supported by BioStudies improves global sample data integration; creates real-time data visibility and access; enables the connection to bioprocess- ing data; tracks sample consent for sample usabili- ty; provides intuitive search and delivers custom data reporting. With BioStudies, researchers can quickly identify the right sample characteristics for medical research studies using integrated sample data analytics and request access to high-quality samples and data sets, which in turn reduces research costs and speeds medical therapies to mar- ket faster (Figure 14).


Many of today’s current methods for cryopreserva- tion of samples require chemicals and mainte- nance. Isopropanol (IPA) containers used for cryo- genic freezing require costly alcohol replacements every five uses, can be cumbersome to handle and may have inconsistent freezing rates. As an alterna- tive, Corning® (www.corning.com) CoolCell® is a


Drug Discovery World Summer 2017 35


reusable, alcohol-free freezing container, which controls the rate of freezing to -1˚C/minute when placed in a -80˚C freezer to uniformly freeze cells at a lower cost of use. The patent-pending CoolCell® technology utilises a thermo-conductive alloy core and highly insulative outer material to control the rate of heat removal and provide repro- ducible cell cryopreservation with high cell viabili- ty. In addition, Corning 1D/2D barcoded cryogenic vials allow for efficient management and manipu- lation of multiple storage tubes. Laser-etched 2D barcodes on the bottom of the vial, as well as linear barcodes on the side of the vial, can be used for


Figure 13


Bluechiip technology advantages and differentiation points


Figure 14 Brooks Life Sciences BioStudies® Biobank Data Management System – overcoming data integration challenges through a centralised technology platform


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