reducing the intake of a diet containing that compound. The present study indicated that a diet supplemented with 50 mg/kg neotame reduced the performance of weaned pigs through reduced feed intake, for there were no neotame-related changes in FCR during the experimental period and thus neotame does not alter nutrient digestion, metabolism, or assimilation. It is, however, necessary to evaluate the safety of neotame before its application as a feed additive. On the other hand, the effects of sweeteners differ widely possibly
because pigs have different preferences for different sweeteners and doses in the diets differ. The responses are also likely to be affected by the age and weight of the pig at weaning and by the composition of the basal diet.
Organ health and metabolism Haematological parameters could play an important role in evaluating the physiological status and assessing injuries that are caused by certain substances. In this study, for pigs fed 50 or 500 mg/kg neotame, no detrimental effects were observed on haematological parameters, which are indicators of infectious diseases, anaemia, and coagulation function. Serum biochemical parameters reflect the health status of the kidney and liver functions and lipid metabolism. No significant deviation from the control group in serum biochemical
parameters was found in pigs offered diets containing either 50 or 500 mg/kg neotame. Similarly, a histological examination of the liver and kidney and an organ index revealed no toxicological damage.
Faecal microbiota In a similar study, published in the Canadian Journal of Animal Science, the supplementation of piglet diets with 0.02% neotame resulted in an increased number of faecal Lactobacillus, suggesting the probiotic and prebiotic benefits of neotame in piglet diets. An optimized GIT microbiome in piglets is especially important for growth and disease resistance. The piglet body provides a permissive habitat and nutrients for bacterial colonization and growth. In return, probiotic bacteria produce prebiotics such as short-chain fatty acids and bacteriocins that benefit piglets by enhancing their growth and reducing their risk of enteric infection by pathogens.
Conclusion “Our results showed that 18.0–20.4 mg/kg, 22.0–22.9 mg/kg and 20.7–21.7 mg/kg neotame optimized the intake and growth rate of pigs after weaning during phase I (day 1–22), phase II (day 23–35) and entire experimental period (day 1–35), respectively. Our results also showed that pigs tolerated up to 500 mg/kg neotame without adverse effects on their health,” the researchers concluded.
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FEED COMPOUNDER MARCH/APRIL 2023 PAGE 23 AQUAFL
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