Contents


negative reactions in certain people, and how medical science and wider society have to work together to get populations on board with vaccination.


33 Mineral salts: indispensable in vaccines Dr Paul Lohmann


35 How 3D printing is revolutionising pharma DFE Pharma


Manufacturing


36 Mind the skills gap There’s a skills shortage in the world of cell and gene therapy. This isn’t news; the problem has endured for years without a solution – but could that be because there isn’t one? Peter Littlejohns asks academic turned consultant William Janssen, who has spent a lifetime researching and applying cells with therapeutic applications in cancer clinics; Sarah Stoll, director of biomanufacturing consultancy Project Farma; and James Kusena, head of bioprocessing at cell manufacturing technology start-up MicrofluidX, whether the talent shortfall can be overcome.


39 Safe and effective washing with acetone LAST Technology


41 A GxP data fabric: the foundation of AI in pharma manufacturing Aizon


42 High-tech filtration solutions BEA Technologies


60


45 Ensuring the integrity of pharmaceutical packaging Pfeiffer Vacuum


46 Operate with the agility you need in the facility of the future


Rockwell Automation Supply chain & logistics


50 Hashgraphs for healthcare Developing Covid-19 vaccines was a huge challenge, but successfully distributing them is another. Long- touted as revolutionary for pharma, distributed ledger technology has the potential to greatly improve supply chains. Mae Losasso speaks to Tom Screen, technical director at Everyware UK, to find out how this technology has been implemented by the NHS to


monitor the storage and supply of the vaccine – and why it might be key to the future of healthcare.


53 End-to-end solutions for cold chain logistics Thermo King


55 Delivering medical supplies to the four corners of the world Turkish Cargo


56 Chain reaction


Covid-19 has highlighted the need for pharmaceutical supply chains to be resilient and flexible. Building them to be agile and adaptive mitigates risk from sudden changes in supply and demand, but what are the key factors to achieve this and what lessons have been learned from the pandemic? Lynette Eyb asks supply chains expert Dr Liz Breen, director of the Digital Health Enterprise Zone at the University of Bradford.


Packaging 50 World Pharmaceutical Frontiers / www.worldpharmaceuticals.net


60 Counterfeit and proper The health crisis created by Covid- 19 has created further opportunities for black market medicines to be sold to worried populations. Jackie Pullman explores how Novartis, through its work with the PharmaLedger consortium, is adding a blockchain-powered layer of authenticity to pharma packaging by talking with Daniel Fritz, a supply chain technology architect at the company.


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