APPLICATIONS: Pharmaceuticals Protein Particles in Nanopharmaceuticals


K-kit can be used for characterizing protein particles in Nanopharmaceuticals by imaging the particle morphology, size and size distribution, to evaluate drug formulation or conduct any bioequivalence study.


Protein particles (Paclitaxel @ Albumin) in Abraxane®


* US FDA approved 2005


Albumin Shell (Excipient)


• Hydrophobic • M.W. 854 Da


Paclitaxel (Drug)


* Scale bar: 200 nm Abraxane in saline _ size & size distribution (D10/ D50/ D90)


• Total calculated particle #: 319 • Average size: 85.1 nm • Standard deviation: 27.0 nm


Parameter D10 D50 D90


Span: (D90 - D10) / D50


Size (nm) 55.6 80.1


122.2 0.831


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