APPLICATIONS: Biology


EXAMPLES Multiple Loading Application


With an unibody structure, K-kit can be capable of multiple liquid loadings that are usually required in some significant biological applications such as negative staining for low contrast bio samples, studies of catalytic reaction mechanisms, or image-based immunoassay development.


Liquid-TEM Observation Sample Preparation & Observation:


• Hitachi HT7700 TEM @ acc. voltage of 100KV • Gap0.2um/SiN30nm K-kits to be applied • With negative staining by 0.25% UA (Uranyl Acetate)


1st K-kit loading with liquid A (such as liposomes/LDL).


The K-kit prepared in dry mode for liquid A


Extracellular Vesicles (Exosomes) of Platelets The extracellular vesicles which released from platelets could be observed by using K-kit.


2nd K kit loading with liquid B (such as staining solution).


The K kit in dry mode again for liquid B.


E.coli The nucleoid of E.coli could be observed in TEM using K-kit


Collagen Collagen molecules aggregate in liquid to form nanofiber structures.


Doxorubicin @liposome


Liposomes could be clearly observed in TEM, by using K-kit with negative staining


4 Collagen The packing structure of collagen could be observed in TEM using K-kit.


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