VIROLOGY
2.0 2.5 3.0
0.0 0.5 1.0 1.5
2500 Region Andean Subregion 2000 1500
Central American Isthmus and Mexico Latin Caribbean Non-Latin Caribbean North America Southern Cone
1000
500
0 1980 1985 1990 1995 2000 Fig 2. PAHO Epidemiological update of dengue and severe dengue in the Americas.7 for diagnosis.8 It is therefore not at all
surprising that dengue, among others, remains on the WHO Neglected Tropical Diseases List.9
Dengue disease Humans are the primary hosts of this zoonotic disease and once a mosquito is infected it can transmit the dengue virus for life.10
Following a mosquito
bite the incubation period for the virus is between three and 14 days. With almost four billion people living in an at-risk area, dengue is often the leading cause of viral illness within these areas.10
Each year up to 400 million
people globally are infected by the virus, with around 100 million showing clinical symptoms. Disease statistics indicate around 40,000 die from severe dengue disease each year.10
with one serotype provides long-term immunity to that serotype.2
Infection However,
secondary infection from another serotype can cause disease. Secondary infections are usually more severe and increase the risk of severe dengue disease.10
Dengue is an acute viral illness and diseases caused vary in their severity, with up to 80% of dengue virus infections being asymptomatic or only producing a mild self-limiting illness.4
Mild symptomatic dengue fever is characterised by a sudden onset of high fever with severe joint and bone pain and is commonly termed ‘breakbone fever’. The symptoms last for between three and seven days and it is common to be accompanied by severe headaches, lassitude, myalgia, diarrhoea, vomiting, rash, and a metallic taste in the mouth.5
With
Gain time
S-Monovette® Safe. Fast. Sustainable.
Gain with the S-Monovette®
• Reduce time and costs for personnel and material with a minimised haemolysis rate
• Utilise the advantages of a dual system for all vein conditions
• Reduce your CO2 emissions,
waste volume and disposal costs considerably
Blood
collection with the
S-Monovette® & Tempus600® 2005 2010 2015 2020 2025
Gain with Tempus600®
• Shorten the total turnaround time (ToTAT) for clinical specimens
• Save valuable time for your staff with the easy, immediate transport of specimens and relieve existing transport systems
• Take the next step towards laboratory automation
Learn more about the synergy of S-Monovette® & Tempus600®
s-monovette-tempus600.
sarstedt.com
SARSTEDT Ltd. · Optimus Way · Optimus Point · Leicester LE3 8JR · Tel: +44 116 235 9023 · Fax: +44 116 236 6099 ·
info.gb@
sarstedt.com ·
www.sarstedt.com
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