CELL LINE COLLECTION
Celebrating four decades of cell cultures at ECACC
To mark its 40th anniversary, Dr Jim Cooper, the European Collection of Authenticated Cell Cultures’ Operational Lead, looks back at the department’s fascinating history, the collection’s achievements and impact on the scientific community and public health.
Established in 1984 to support the research community, the European Collection of Authenticated Cell Cultures (ECACC) has diversified over the last 40 years to become one of the most respected collections of authenticated cell cultures in the world.
Cell culture beginnings ECACC’s journey began in the 1970s
when the field of cell culture was in its infancy. The Porton Microbiological Research Establishment (MRE) managed several small collections of cells for research purposes. Following the creation of the Centre for Applied Microbiology and Research (CAMR) in 1979, these collections were consolidated into the National Collection of Animal Cell Cultures (NCACC) to provide
a centralised repository for disease research in 1984. Up until this point cell lines were obtained from friends and colleagues or from the American Type Cultures Collection (ATCC). Funding from the Department of
Trade and Industry helped create a repository at Porton, and in 1985 the National Collection of Animal Cell Cultures became the European Collection of Animal Cell Cultures. The next decade was a period of scientific growth, leading to the development of a human genetics service and novel molecular identity tests. Many of the assays and techniques used within ECACC today were developed in this period. These technologies drove the adoption of pioneering automated nucleic acid extraction and sample processing for high-throughput projects.
Funding from the Department of Trade and Industry helped create a repository at Porton, and in 1985 the National Collection of Animal Cell Cultures became the European Collection of Animal Cell Cultures
The ECACC team during the 1990s. 38 DECEMBER 2024
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