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greater surface area to volume ratio. It is also significantly more hydrophobic compared to S. cerevisiae. Additionally, the distribution of various glycoproteins in the yeast cell wall var- ies, suggesting P. guilliermondii has a different cell wall struc- ture and composition to S. cerevisiae. These particularities may be associated with significant differences in how the two yeast cells behave when used in animal feeding. The function of P. guilliermondii and associated influence on physiological and performance parameters have been as- sessed across a variety of animal species. This body of re- search has focused on looking at the impact that may be as- sociated with P. guilliermondii on the immune system, pathogen load, gastrointestinal health and performance, especially during stress and pathogenic challenges.


Promoting improved performance in swine In vitro P. guilliermondii has been demonstrated to be effec- tive in binding or aggregating swine-specific strains of Es- cherichia coli and Salmonella enterica, and to a greater extent than S. cerevisiae-based solutions (see Figure 1). P. guilliermondii has been studied in vivo in both experimental and commercial swine facilities and been demonstrated to be associated with various beneficial impacts on performance. Of note, supplementing the gestation and lactation diets of sows and gilts with a P. guilliermondii feed additive has been associated with improved sow reproductive parameters related to fecundity and piglet performance. For example, in three separate studies, more pigs were weaned per litter among sows that received P. guilliermondii supplementation,


compared to sows not receiving any P. guilliermondii supplementation (see Figure 2).


Novel yeast leading to feeding efficacy P. guilliermondii is a novel yeast with unique morphological properties influencing its efficacy in animal feeding. Research has demonstrated its effectiveness in swine, especially in sows during gestation and lactation to support reproduction and piglet performance.


References available on request.


Figure 2 - Comparison of number of piglets weaned from sows that received P. guilliermondii supplementation during gestation


and lactation to control sows, in three separate studies. 12.5 12.0 11.5 11.0 10.5 10.0 9.5 9.0


Bass et al. 2019 Control sows Thayer et al. 2020 Data on file 2020 P. guilliermondii sows ▶ PIG PROGRESS | Volume 38, No. 3, 2022 25


Supplementing sow and gilt di- ets with P. guill- ermondii has been associated with piglet per- formance.


Number of piglets weaned


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