FEED ADDITIVES ▶▶▶
A novel whole yeast for feed applications
In animal nutrition in the last 20 years, the yeast Saccharomyces cerevisiae has developed a name for being beneficial to pigs. Yet the world of yeasts is much larger – Pichia guilliermondii is a relatively novel type of yeast with promising potential for use in swine feed applications.
BY SARAH COOPER, ADM ANIMAL NUTRITION Y
180 160 140 120 100 80 60 40 20 0
Mannose 0.05 M
Control 0.05% 0.075% 0.1% 0.05% 0.075% 0.1% 0.05% 0.075% 0.1% S. cerevisiae
S. cerevisiae hydrolysed Pichia guilliermondii Source: Cardozo et al., 2018.
easts have been fed to animals for over 100 years due to their nutritional richness and for their re- ported effects in supporting health and growth performance. Yeasts, yeast-derivatives and
yeast-containing products are now extensively given in ani- mal feeds around the world. There are literally hundreds of different yeast-based animal feed products available. In recent years with the tightening of restrictions related to the use of growth-promoting antibiotics in animals and con- cerns about antimicrobial resistance, there is growing interest in evolved management practices, including the use of
Figure 1 - Aggregation capacity of three products against swine strains of E. coli and S. enterica. 200
E. coli S. enterica
in-feed supplements that may help to optimise animal per- formance. Yeast cell walls contain various bioactive components such as β-glucans and mannan oligosaccharides, which have been demonstrated to have beneficial impacts across various spe- cies. Several studies have shown that dietary β-glucans inter- act with intestinal cells, affecting modulation of the intestinal immune response. Mannan oligosaccharides have been demonstrated to bind and limit the colonisation of intestinal pathogens, with beneficial consequences related to gastro- intestinal health and performance. Taxonomically yeasts are broken up into 60 different genera, and within these genera are about 500 different species. Only a few yeast species have commercial importance. For animal feed applications, Saccharomyces cerevisiae is the most commonly used yeast.
Pichia guilliermondii Pichia guilliermondii is a novel yeast with unique morphology, structure and consequent activity which has become availa- ble for use in feed applications only recently (CitriStim). The morphology, cell wall structure and composition of yeast cells used as animal feed additives are of interest as they influence the way the yeast cell behaves in the host’s intestinal environ- ment, interacting with intestinal epithelium and luminal con- tents and containing pathogens. The comparative morphology and physical characteristics of P. guilliermondii and S. cerevisiae have been assessed in a side- by-side study. There are significant differences between them: P. guilliermondii is a smaller cell and as such has a
24 ▶ PIG PROGRESS | Volume 38, No. 3, 2022
Percentage aggregaion, %
PHOTO: PANCOSMA | ADM
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