Enterococcus faeciumE. coli (F18) 


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Control Probiotic


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04 Incubation of E. coli (hours)


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Figure 2 - Reduction of adherence of E. coli (F4) to intestinal epithelia by probiotic strain Enterococcus faecium (NCIMB 11181).


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diarrhoea in piglets. The pathogen will then excrete toxins, stimulating the production of electrolytes and fluid into the lumen and causing diarrhoea. Figure 1 shows how the probiotic strain, Enterococcus faecium (NCIMB 11181), could inhibit the growth of E. coli. Figure 2 shows that the same probiotic strain reduced the adherence of the pathogenic E. coli (F4) strain to the intestinal epithelia by up to 60%. Such a reduction in adherence of E. coli can lead to a reduction in the prevalence of diarrhoea among piglets. An in vivo study in weaned piglets fed either a standard diet or a diet including this probiotic strain showed a reduction in the occurrence of diarrhoea (see Figure 3).


Therapeutic use of zinc oxide In the near future, the therapeutic use of zinc oxide will be banned in Europe, and the industry is looking for solutions to control or prevent post-weaning diarrhoea. Findings shown here suggest that probiotics, such as Enterococcus faecium (NCIMB 11181) could be part of the overall solution. Howev- er, it is important to mention that the degree to which differ- ent probiotic strains can prevent or limit the adhesion of pathogens or inhibit pathogens is strain-specific. Strains matter.


References are available on request.


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Figure 3 - Reduction in diarrhoea occurrence in weaned piglets fed a diet with or without the probiotic strain Enterococcus faecium (NCIMB 11181).


Occurence of diarrhoea 100


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0 Control Probiotic ▶PIG PROGRESS | Volume 36, No. 7, 2020 31


PHOTO: CHR. HANSEN % % Log10 E. coli


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