USDA-ARS Researchers Introduce Treatment To Prevent Parasites In Sheep T


he U.S. Department of


WASHINGTON, D.C. Agriculture's


Agriculture Re-


search Service (ARS) announced a ground- breaking treatment that prevents


anemia,


weight loss, poor wool and meat production, and even death in sheep. ARS researchers part- nered with Virginia


Tech and the University of Massachusetts' Med- ical School to solve H. contortus parasite in- fection, which also hap- pens to be the number one health problem in the U.S. sheep indus- try. The parasite infects the stomach of rumi- nant mammals, feeding and interfering with di- gestion, before ulti- mately affecting the animal's overall health


and stability. "The H. contortus par-


asite has developed re- sistance to virtually all known classes of anti- parasitic drugs," said ARS Researcher Dr. Joseph Urban, who lead the research team in testing and implemen- tation of a para-probi- otic treatment to kill the parasite that causes H.contortus. The worm parasite


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protect an even larger population of animals across the country. "Para-probiotics rep-


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said Dr. Raffi Aroian, a professor in the Molec- ular Medicine program at the University of Massachusetts' Medical School. "The develop- ment of new therapeu- tics for this issue has been extremely difficult to come by and I look forward to watching this new advancement unfold in the global and domestic industry." This project was sup-


ported by the National Institutes of Health/Na- tional Institute of Al- lergy and Infectious Diseases; and the Agri- culture and Food Re- search


Initiative


Competitive Grant from the USDA's National In- stitute of Food and Agriculture. The Agricultural Re-


search Service is the U.S. Department of Agriculture's chief sci- entific in-house re- search agency. Daily, ARS focuses on solu- tions to agricultural problems


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Roundtable Discussions 54 Phd.’s


mates within the ani- mal and its fertilized eggs pass through the animal's waste into the soil. The larvae then de- velop to re-infect other unsuspecting animals, spreading the infection throughout a pasture and creating a cycle of infection that hinders animal growth, develop- ment and production. "This is a major prob- lem and the newly-de-


veloped treatment is de- rived from bacteria nor- mally found in the soil that can produce a pro- tein that binds to recep- tors in the intestine of the parasite," said Dr. Urban. "The treatment will then kill the para- sites and reduce debili- tating infection in adult sheep." "When the treatment


was given to infected sheep at Virginia Tech


interest


there was a rapid and dramatic reduction of parasite reproduction and survival, without any negative effect ob- served in the sheep." said Dr. Anne Zajac, professor of parasitol- ogy at Virginia Tech's Virginia-Maryland Col- lege of Veterinary Medi- cine. Para-probiotics


are


"inactive probiotics," or good bacteria that can still provide health ben- efits. Despite the grow- ing


in para-probiotic use,


these types of treat- ments are not commer- cially available. The treatments are cur- rently under review by the U.S. Food and Drug Administration and will likely be commercially produced amounts


once


in large ap-


proved. This will help to The parasite infects


the stomach of ruminant mammals, feeding and


interfering with digestion, before ultimately affecting the animal's overall health and stability.


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