project has resulted in over 80 publications, and succeeded in attracting almost 900 users,
achievement life
AT A GLANCE in
locations ranging from Afghanistan to Vietnam. Another laudable
becoming one of the largest virtual
supporting
research and, of course, having
contributed is
organisations science
to several notable projects. underlying be
One recent study accessing grid facilities examined the sting of ocean-dwelling cone snails, with the aim of harnessing the biological mechanisms
at
watchv=1tWduGtNRYg. NMR analysis
on paralysis
communication scientists
http://www.youtube.com/ By
peptides by channels in Project Information
Project Title: WeNMR: A worldwide e-Infrastructure for NMR and structural biology
to
generate a new anaesthetic. The video can found
conducting contained
within the snail’s sting, which inflicts numbing
in Utrecht have been able
comprehend how it operates at the molecular level. Equipped with this mastery, scientists
could attempt to recreate and
“WeNMR allows researchers to reach EU computational resources and that of rest
the of the world,” says Bonvin.
“Computational jobs can be sent to the grid in South America and Asia, and we have recently linked with the US Open Science Grid
(OSG). Locally, we’ve maintained
direct connections with the EGI (European Grid
Initiative) from inception. A
fundamental strength of our approach is that users don’t need to worry about settings or strict procedures and can focus on their own scientific problems. We provide solutions for people to use top- flight software, which is often complex, and requires expertise in computing, administration, systems and installation to fully utilise. Our growing community finds this very attractive”. Now in its third year of operation, WeNMR has achieved
notable recognition. MAIN CONTACT The
enhance some of these natural attributes, synthesising an effective painkiller. Within the research community, there is
presently much speculation over the EU’s Horizon 2020 ambitions, in which WeNMR hopes to play a meaningful part. Although the focus of policy makers is often on the most powerful supercomputing hardware their nations possess, Bonvin insists that the EU must support grid access for projects of all scales. “Many researchers are conducting smaller – but nonetheless
projects, which don’t require access
important – to
intensive HPC, but could benefit from IT resources offered via the grid. This is the community we want to target,” says Bonvin. “Scientists are developing very specific tools to obtain small, yet fundamental pieces of information about biological systems. You need to put all of the fragments together to obtain a complete, holistic picture.”
Photo: @ Ed van Rijswijk 18
Prof. Dr. Alexandre M.J.J. Bonvin Alexandre Bonvin (1964) studied Chemistry at Lausanne University and obtained his PhD at Utrecht University (1993). After two post-docs at Yale University (Prof. A.T. Brunger) and at the ETHZ (Prof. W.F. van Gunsteren) he joined Utrecht University in 1998 where he was appointed full professor of computational structural biology in 2009.
Project Partners: Bijvoet Center for Biomolecular Research, Utrecht University
Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe Uni- versity, Frankfurt am Main
Interuniversity Consortium for Magnetic Resonance on Metal- loproteins (CIRMMP), Florence University
National Institute of Nuclear Physics, Padua
Radboud University, Nijmegen University of Cambridge (UCAM)
European Molecular Biology Laboratory (EMBL)
Spronk NMR Consultancy (SpronkNMR)
Academia Sinica (AS), Taipei
Contact: Tel: +31-30-2533859 Email:
a.m.j.j.bonvin@
uu.nl Web:
www.uu.nl/staff/AMJJBonvin
disrupting neurons, to
future
Project Objective: WeNMR aims at bringing together complementary research teams in the structural biology and life science area into a virtual research community at a worldwide level and provide them with a platform integrating and streamlining the computational approaches necessary for NMR and SAXS data analysis and structural modelling.
Project Duration and Timing: Three years: November 1st, 2010 – November 1st 2013. The portal will remain operational beyond the project end date.
Project Funding: Three years: November 1st, 2010 – November 1st 2013
we -nmr Insight Publishers | Projects
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