NEWS FROM THE UNIVERSITIES
Bacteria resistant materials win research funding
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Researchers at the University of Nottingham who discovered a group of new materials capable of repelling bacteria have won a research award worth £2 million to fi nd out why. Their bacteria resistant polymers could lead to a signifi cant reduction in hospital infections acquired through indwelling devices such as catheters, intravenous tubes and artifi cial joints. Morgan Alexander, Professor of Biomedical Surfaces,
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and Paul Williams, Professor of Molecular Microbiology, have each received a Wellcome Trust Senior Investigator Award for a joint project to understand why bacteria take such a dislike to their newly discovered polymers. Professor Alexander said, “We have a challenging five years ahead of us. The polymer material chemistries could not have been predicted from our current understanding of bacterial responses to materials. We will develop new analytical approaches to elucidate the mechanisms by which these polymers resist bacterial attachment encompassing the material and the cells.”
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The researchers found that by coating silicone devices with these materials there was a reduction of nearly 97 per cent in the surface area covered by bacteria compared with commercially available devices. The materials have been licensed to Camstent Ltd, with whom the University is developing coated urinary catheters. The first clinical trial is being prepared for this autumn.
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