chromatography • spectroscopy 23
Fig. 1. Agilent says its 1260 Infinity Hybrid SFC/UHPLC system is the first commercial instrument that performs both supercritical fluid chromatography and ultra high-performance liquid chromatography.
Analysing such samples usually requires additional sample preparation (dilution/concentration) and a second injection, sometimes with recalibration. Te new detector eliminates these time-consuming efforts, acquiring all sample information in a single run - and significantly increasing productivity by reducing turnaround time.
Te Agilent solution extends the upper linearity level from two to typically six absorbance units. Tis allows injection of three times more sample while also reducing detector noise by 10 times.
Te result is up to 30 times higher sensitivity for simultaneous analysis and quantification of main compounds and impurities.
“We are excited by the new 1200 Infinity Series HDR-DAD as it simplifies the quantitation across many LC applications,” said Christian Gotenfels, Agilent product manager. “For example in pharmaceutical analysis, the Agilent solution facilitates quantitation of active pharmaceutical ingredients and respective impurities of fixed- dose combinations in a single run.”
Advances in chromatography and spectroscopy
The best new releases focus on lower detection limits, better precision and improved productivity.
Les meilleures nouveautés sont axées sur des limites de détection plus basses, une meilleure précision et une productivité améliorée.
Die besten neu erschienen Produkte zielen auf niedrigere Nachweisgrenzen, höhere Präzision und gesteigerte Produktivität ab.
A
gilent Technologies has introduced the 1200 Infinity Series high
dynamic range diode array detector for liquid chromatography. Te company says it delivers 30 times wider linear UV-range and up to 30 times higher sensitivity than previous detectors, making it suitable for analysing mixtures that contain widely different concentration levels.
A second new introduction from Agilent is the1260 Infinity Hybrid SFC/UHPLC system. It is the first commercial instrument that performs both supercritical fluid chromatography and ultra high- performance liquid chromatography (Fig. 1).
Tis enables intelligent screening for the most suitable method of separation and delivers comprehensive information for complex samples and impurity analysis.
“Now chromatographers can switch between UHPLC and SFC on the same system without making a single hardware or method change,” said Stefan Schuette, Agilent senior marketing director, liquid chromatography business. “Users can have great confidence in the results from using these two
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