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Advantages of Simultaneous Imaging


condensers, and other high-quality optical components. Differential interference contrast, phase contrast imaging, or fluorescence microscopy can be used to expedite the identification of individual cells and features of interest. When combined with “Point and Shoot” capabilities, the optical images can be used to quickly and precisely position samples directly under the tip of an AFM probe.


References [1] Nowakowski et al., Biochimica et Biophysica Acta 1514(2) (2001) 170–76.


[2] Goldsbury et al., Current Protocols in Protein Science (58) (2009) 171–217.


[3] Madl et al., Ultramicroscopy 106 (2006) 645–51. [4] Schmitz et al., Anal Chem 69(6) (1997) 1012–18. [5] Han and Lindsay, Appl Phys Lett 72 (1998) 1656. [6] Stroh et al., PNAS 101 (2004) 12503–12507. [7] Gaboriauda et al., Colloids and Surfaces B: Biointerfaces 62(2) (2008) 206–13.


[8] Baudin et al., Nat Protoc 2(3) (2007) 481–485. [9] Masters, Nature Reviews Cancer 2 (2002) 315–319.


[10] Frohlich, J Vis Exp 17 (2008) 844. [11] Wolosewick and Porter, American Journal of Anatomy 149(2) (1977) 197–225.


[12] Adamson et al., Journal of Physiology 539 (2002) 295–308. [13] Metcalf et al., J Cell Sci 1(121) (2008) 19–27. [14] Vandekerckhove et al., EMBO J 4(11) (1985) 2815–18. [15] Weghuber et al., Anal Bioanal Chem 397(8) (2010) 3339–47.


SPECTROSCOPY OF


MICROSCOPIC SAMPLES


CRAIC Technologies UV-visible-NIR microscopes and microspectrophotometers are used for imaging and spectral analysis of sub-micron sized features with absorbance, reflectance, fluorescence, emission and polarized illumination. Capabilities include film thickness measurements, colorimetry and high resolution imaging in the UV, visible and NIR regions. Rapid & accurate spectra & images of microscopic samples: The Perfect Vision for Science™


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For more information, call 877.UV.CRAIC or visit our website at www.microspectra.com


©2011 CRAIC Technologies, Inc. San Dimas, California (USA).


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