Carmichael’s Concise Review Coolled_Ad 114x89_MicrospToday:Layout 1 02/06/2011 17:03 Page 1 If the wings and the helmet are serial homologues, then
their development must rely on a shared genetic program. A search for shared molecular signatures revealed that a transcription factor (Nubbin) had a spatial deployment during development that corresponded to that seen in wings. Tere was also evidence suggesting that the helmet escaped the ancestral repression of wing formation imparted by a member of the Hox gene family, which sculpts the number and pattern of appendages. So how did this apparent appendage evolve into such
a morphologically diverse helmet? Prud’homme et al. convincingly propose that, in contrast to wings, the helmet escaped the stringent functional requirements imposed by flight. If the helmet is accepted as a pair of appendages equivalent to wings, then this will be the exception to a pattern that has existed for 250 million years!
References [1] B Prud’homme, C Minervino, M Hocine, JD Cande, A Aouane, HD Dufor, VA Kassner, and N Gompel, Nature 473 (2011) 83–86.
[2] Te author gratefully acknowledges Dr. Benjamin Prud’homme for reviewing this article.
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www.microscopy-today.com • 2011 November
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