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PRODUCTS

MATHEMATICS, SIMULATION AND MODELLING

Tackling biological system simulation

The MathWorks has launched the latest version of SimBiology, with new features and enhanced capabilities, including multiple dosing schemes, for pharmacokinetic/ pharmacodynamic modelling and simulation of biological systems. Pharmacokineticists and computational biologists use SimBiology to create, simulate, and analyse both mechanistic and PK/PD models in one software environment. SimBiology simplifies the modelling workflow and reduces simulation and fitting times by providing a graphical interface for mechanistic models. With the new enhancements, users can select from multiple fitting algorithms, including stochastic approximation expectation- maximisation (SAEM), and compare

results with other fitting algorithms. The tool’s graphical interface also now enables users to apply multiple dosing schemes to their models, eliminating the need to manually schedule dosing.

New features include: SAEM algorithm for fitting population data; support for applying multiple dosing schemes to a model; enhanced support for importing NONMEM formatted files; and a new mode for accelerating simulation.

www.mathworks.co.uk

Updated simulation software

Integrated Engineering Software has released version 9.0 of its simulation software, which includes general enhancements to make accurate modelling easier and faster. Visualisation tools have had major enhancements including being able

to pre-define output/output manager structure for the natural flow of design/simulation enabling better management of multiple plots. There are faster and more robust geometry operation capabilities in both 2D and 3D programs and an Enhanced Time Modeler to simulate various types of signals and sources in time domain. Integrated has enhanced the coils/ windings feature in its magnetic programs and users can now evaluate the force/torque on bodies due to external static. For customers using the Tecplot plotting package to generate 2D and 3D plots from raw calculated data, format data export is available. Users who choose to view and manipulate their plots in Tecplot can export plots from Integrated applications to be opened in Tecplot, where they can further manipulate and view the data.

Transient capabilities have been extended to Integrated’s 3D programs electrostatic (Coulomb), eddy current (Faraday) and heat transfer (Celsius) solvers. There have been significant improvements made to matrix solvers and pre-conditioners for large, dense or sparse matrices, generated from BEM or FEM.

Lorentz, Integrated’s 2D/3D electromagnetic analysis and hybrid simulation software, has been upgraded with a new Graphical User Interface (GUI) and simulation flow. It has an improved emission model with new combined emission model, enhanced ODE solver and ray- geometric intersection methods. Due for release later in 2010, Chronos is Integrated’s powerful new time domain field solver for modelling RF and antenna applications.

www.integratedsoft.com

More new products online at www.scientific-computing.com/products

Presents the 9th Annual

Two Day Conference: 28th-29th September 2010 Pre-Conference Focus Day & Workshops: 27th September 2010

Venue: The Marriott Hotel, Amsterdam, The Netherlands

Early Booking Discounts Available

Save up to €550

Visit the website for more information

& Advanced Laboratory Solutions

www.elnforum.com/SCW

Increase your research effi ciency, accelerate workfl ow and enhance geo-separate collaboration by establishing a clear e-laboratory environment in your company

Expert Speaker Panel Includes:

Conference Chairman: Seth Pinsky, Director Scientifi c Informatics and

Automation, Abbott Laboratories

Keynote Presentation: Jim King, Director, R&D Business Technology,

Pfi zer Diversifi ed Businesses

Martin Vanderlaan,

Director, Analytical Operations, Genentech

Dr Ralf Bitschenauer,

System Analyst, Boehringer Ingelheim Pharma GmbH

Ralph Haffner,

Head of Scientifi c Information Systems, Roche

54

SCIENTIFIC COMPUTING WORLD JUNE/JULY 2010

“Very valuable, learned a lot, inspired.”

Raquel Dias Miranda, Novartis Pharma AG

Free Online Resources

Free podcasts, articles and more available to download online CALL: +44 (0)20 7368 9300 / 0800 652 2363

EMAIL: enquire@iqpc.co.uk VISIT: www.elnforum.com/SCW

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