CHEMICALS & PHARMACEUTICALS u HRS Heat Exchangers


important to consider how user-friendly the control systems for the CIP are. For example, are they part of the overall


control interface or a separate system? Another key element of an effective system is monitoring and validation of the cleaning results for traceability and due diligence purposes, and from the beginning the design of the equipment should allow this to be done in an effective manner.


TYPICAL CIP PROCESSES Most CIP employs a similar set of operations, including: •


Pre-rinsing – to remove large debris and residues


•


• •


• • •


Detergent cleaning – to remove attached dirt and soiling using a caustic detergent Rinsing – to remove detergent and dirt


Optional acid cleaning – if required to remove scaling or alkaline residues


Rinsing – to remove the acidic cleaning agent


Disinfection – heat or chemical treatment to disinfect the equipment


Final rinse – to remove all traces of chemicals and prevent contamination


These steps may be combined or used in


different ways. For example, using detergent at high temperatures may clean and disinfect equipment at the same time, or using steam may reduce the need for chemical detergents. Depending on the design of the system, and the


20 June 2023 Irish Manufacturing


CIP systems should ensure that no cleaning fluids or contaminants remain in the equipment – ensuring safety, and by reducing the effort and downtime required for cleaning, they also ensure production cycles are efficient and cost-effective.


risk of contamination, cleaning solutions may be reused multiple times or discarded immediately. There may also be differences between CIP and SIP (sterilise-in-place) systems. While the actual cleaning regime used will depend on a number of factors, including the type of product and the design of the machinery in question, in many situations it is preferable to rely on water alone (together with temperature, pressure and agitation) rather than additional cleaning chemicals which could present a contamination risk. In general, the higher temperatures and


greater kinetic energy provide more efficient cleaning, but the duration of the CIP cycle will be optimised according to the properties mentioned above. Where detergents are required, one of the most common is caustic soda (NaOH), although many other alkali- and acid-based chemicals are available depending on the nature of the product and residues which need to be cleaned.


Alkali materials are generally more effective against proteins and fats, while acids perform better where salts need to be removed. For sugars, water remains one of the most effective cleaning mediums.


HRS CIP SYSTEMS HRS offers two types of CIP (and SIP) systems. The first are those which are integrated into other systems, such as HRS pasteurisers and sterilisers, as well as our Aseptic Block Series and aseptic fillers, for example. The second is the HRS series of stand-alone CIP and SIP systems. These are available with single (ST) or


multiple tanks, which are heated with an HRS K Series heat exchanger. Fully skid-mounted and modular design enables for quick and easy site installation, and the fully automated systems are supplied with a programmable logic controller (PLC) system, which can operate on its own, or be integrated into the factory’s main control system.


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