From the editor


A global objective T


he Asia-Pacific region has always been an important sphere of economic influence in the world but listen to Western political commentary and you’d be forgiven for believing the relationship between the region and


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Clinical Trials Insight Volume 2 2022


Editorial


Editor Peter Littlejohns peter.littlejohns@progressivemediainternational.com Sub-editor Liam Murphy Group art director Henrik Williams Designer Martin Faulkner Production manager Dave Stanford Head of content Jake Sharp


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Client services executive Derek Deschamps Sales manager Nathan Park


nathan.park@progressivemediainternational.com Managing director William Crocker


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its Western counterparts is an adversarial one, characterised largely by the economic rise of China as a threat to US market dominance. But industries don’t operate according to blunt nationalism, they look for business opportunities everywhere, and that’s why our lead story on page 38 looks at why pharmaceutical companies are flocking to countries in the Asia-Pacific to host their clinical trials.


Given the wide variety of locations in which to host trials, the transporting of drugs from manufacturer to site – or patient in the case of a decentralised trial – can add a layer of complexity to the process, especially when those drugs have specific temperature requirements. On page 30, I speak to Richard Peck, former global head of the process- controlled transportation centre of excellence at AstraZeneca, who now runs his own consultancy business, about the ins and outs of shipping pharmaceuticals for trials, when it’s necessary to use air freight, and how environmental concerns factor into the decision. Climate consciousness is a common theme in today’s world, and clinical trials are no exception. On page 48, Monica Karpinski discusses with three experts how reducing the number of studies that don’t have an obvious patient benefit can help offset the environmental impact the industry has, and what constitutes a ‘good’ and ‘bad’ clinical trial.


Study design plays a major role in the outcome of a trial, and adaptive designs have been growing in popularity for certain diseases for a number of years now. On page 34, Mae Losasso speaks to two professors of statistics to find out what benefits adaptive designs have for patients and researchers, and why cancer has been a key use case. Other topics explored in this issue include the digital development of Contract Research Organisations, how wearable technology could have a research benefit and how sourcing strategies must be led by study design.


Peter Littlejohns, editor


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