Contents In this issue 8 News & numbers


The vital headlines and statistics defining the industry.


Drug delivery


10 Down the hatch Vaccination continues to be our best defence against the morbidity and mortality caused by Covid-19, but with the imperative to ‘boost’ the number of antibodies by giving multiple doses each year, the case for a simpler delivery method is growing. Mae Losasso investigates the topic by gaining insight from Jim McManus, director of public health at Hertfordshire County Council, Professor Azeem Majeed, head of department of primary care and public health at Imperial College London, and Dr Sean Tucker, chief scientific officer of Vaxart.


13 The digital health game Some of the most ground-breaking results come when technologies are combined with ambition. Advances in pharmaceuticals will continue to change people’s lives, but there’s a growing interest in complementing them with digital devices designed to encourage and reinforce healthy behaviours. Taking diabetes as an example, Søren Smed Østergaard, Novo Nordisk’s VP of digital health, tells Tim Gunn where the key benefits


of combining pharmaceuticals and digital therapeutics lie, and why there are challenges when it comes to implementing a connected approach.


17 The rise of smart self- injection devices Haselmeier


18 The new generation of platform autoinjectors Owen Mumford Pharmaceutical Services


20 Advancing cartridge-based subcutaneous drug delivery SHL


Manufacturing 22 Better sterile than sorry


40 World Pharmaceutical Frontiers / www.worldpharmaceuticals.net Sterility throughout the 13


manufacturing process is something no pharmaceutical company can overlook, both from a regulatory and a customer care standpoint. That said, the actual processes in place to maintain good manufacturing practices are much more complex than some might think. Benoît Ramond is deeply embedded within the world of contamination control, both as doctor in pharmacy at the University of Paris XI and as head of microbiology and sterile technology expertise for Sanofi. Here, he explains what is required to meet contamination control standards.


25 The power of hydrogen peroxide LAST Technology


26 High-tech


filtration solutions BEA Technologies


28 Advanced instrumentation services Anton Paar


Packaging 29 A glass act


Glass has been the most popular primary packaging choice for drug makers for centuries, a combination of its formulation compatibility and


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